COMPOSITIONS AND METHODS OF TREATING EYE DISORDERS Russian patent published in 2023 - IPC A61K31/192 A61K31/21 A61K35/74 A61K36/28 A61K36/48 A61K36/54 A61K36/75 A61P27/02 

FIELD: medicine, ophthalmology.

SUBSTANCE: invention is intended for the prevention or treatment of symptoms associated with dry eye. The microemulsion composition contains a safe and effective amount of a compound and/or extract having retinol-like properties and/or beneficial effects for use in the treatment of eyes, selected from one or more plant extracts or sources of extracts from plants of the genus Acronychia acidula; source of extracts of bacteria of the genus Actinomyces; and a compound selected from (2E,4E,6E)-7-(1,1,2,2,3,3-hexamethyl-2,3-dihydro-1H-inden-5-yl)-3-methylocta-2,4,6-trienoic acid and 4-(1-(1,1,2,2,3,3-hexamethyl-2,3-dihydro-1H-inden-5-yl)vinyl)benzoic acid and mixtures thereof. The composition also contains an oily component selected from castor oil, corn oil, sunflower oil, mineral oil, silicone oil and mixtures thereof; an emollient or sedative, which is hyaluronic acid or its salt; and an ophthalmologically acceptable vehicle. Microemulsion drops or particles have a maximum size of less than .

EFFECT: using the invention allows to induce, stimulate and/or improve the production/release/delivery/release of hyaluronic acid from the cornea and/or into the cornea.

9 cl, 6 dwg, 5 tbl, 11 ex