USE OF LIPOPEPTIDES AS INHIBITORS OF MEMBRANE FUSION Russian patent published in 2023 - IPC C12N15/86 C07K14/05 C07K14/08 C07K14/165 

Abstract RU 2802823 C1

FIELD: biotechnology.

SUBSTANCE: following is described: the use of antimicrobial cyclic lipopeptides as membrane fusion inhibitors, wherein the lipopeptides are selected from the group consisting of aculeacin A, anidulafungin, caspofungin, fengycin, iturin A, mycosubtilin, and syringotoxin B. In one embodiment, the use of lipopeptides to inhibit fusion of SARS-CoV-2 viral particles with cells is described.

EFFECT: invention expands the arsenal of agents that inhibit the fusion of cell membranes.

2 cl, 5 dwg, 4 tbl, 2 ex

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RU 2 802 823 C1

Authors

Efimova Svetlana Sergeevna

Zarubaev Vladimir Viktorovich

Zlodeeva Polina Dmitrievna

Muryleva Anna Andreevna

Ostroumova Olga Sergeevna

Slita Aleksandr Valentinovich

Shekunov Egor Viacheslavovich

Dates

2023-09-04Published

2022-11-09Filed