PHENYL-2-HYDROXY-ACETYLAMINO-2-METHYL-PHENYL COMPOUNDS Russian patent published in 2023 - IPC C07D213/82 C07D239/28 C07D487/04 A61K31/4418 A61K31/519 A61K31/4965 A61P35/00 

Abstract RU 2804280 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound of the following formula

, where R is selected from the group consisting of and ; X is CH or N; R1 is hydrogen or fluorine; and R2 is C1-C3 alkyl; or to its pharmaceutically acceptable salt. The invention also relates to a pharmaceutical composition having PERK inhibitor activity based on the said compound.

EFFECT: obtaining new compounds and a pharmaceutical composition based on them which can be used in medicine as effective agents for the treatment of prostate cancer.

11 cl, 4 tbl, 9 ex

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RU 2 804 280 C2

Authors

Cifuentes-Garcia, Marta Maria

Garcia-Paredes, Maria Cristina

Dates

2023-09-26Published

2018-04-11Filed