METHOD OF PRODUCING PLATELET-RICH BLOOD PLASMA FOR TREATMENT OF MACULAR RETINAL HOLES Russian patent published in 2023 - IPC A61F9/07 A61M1/36 A61K35/19 A61P27/02 

FIELD: medicine; ophthalmology.

SUBSTANCE: invention can be used to obtain platelet-rich blood plasma (PRP) for the surgical treatment of macular retinal holes. The method includes collecting venous blood, mixing it with an anticoagulant, introducing YCELLBIO-KIT into a test tube with an 18G needle through the paracentral hole in the cap of the test tube. Centrifugation is carried out twice at a rotation speed of 3,400 rpm for 4 minutes. When obtaining a cloudy layer of PRP, without any clear boundaries of the L-PRP layer, additionally, double centrifugation is carried out at a rotation speed of 2,000 rpm for 1 minute, and then a layer of pure PRP is removed at the P-PRP level. The invention reduces the risks of postoperative inflammation by optimizing the cellular composition of PRP selected for surgery from the total volume of PRP obtained in a specialized YCELLBIO-KIT tube.

EFFECT: invention also makes it possible to achieve a good anatomical result (complete closure of the macular hole with restoration of the structural elements of the retina) and persistent positive dynamics of visual function in the early (1st day) and late (6 months) postoperative period, reducing the risk of postoperative inflammation.

4 cl, 3 ex