FIELD: molecular biology.
SUBSTANCE: method for predicting breast cancer metastasis based on a group of long non-coding RNA genes by identifying the methylation of any two out of five markers is described; according to the invention, the markers are the following genes: HAND2-AS1, KCNK15-AS1, MAGI2-AS3, SSTR5-AS1 and SNHG6.
EFFECT: inventive method makes it possible to predict formation of metastases in breast cancer with high specificity and sensitivity.
1 cl, 1 dwg, 3 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR DIAGNOSING OVARIAN CANCER BASED ON A SET OF GENES OF LONG NON-CODING RNA | 2021 |
|
RU2779550C1 |
| METHOD FOR PREDICTION OF OVARIAN CANCER METASTASIS BASED ON SET OF GENES OF LONG NON-CODING RNA | 2023 |
|
RU2825782C1 |
| METHOD FOR DIAGNOSING BREAST CANCER BASED ON A SET OF LONG NON-CODING RNA GENES | 2022 |
|
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| METHOD FOR DIAGNOSING OVARIAN CANCER BASED ON A GROUP OF microRNA GENES | 2018 |
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| METHOD OF DIAGNOSIS OF CLEAR CELL RENAL CELL CARCINOMA AND METHOD FOR PREDICTION OF METASTASIS BASED ON MIRNA GENES GROUP | 2017 |
|
RU2683251C1 |
| METHOD FOR DIAGNOSING BREAST CANCER BY THE LEVEL OF METHYLATION OF THE ZNF177 AND CCDC181 GENES IN SMALL TUMORS | 2022 |
|
RU2789200C1 |
| METHOD FOR PREDICTING NON-METASTATIC SURVIVAL IN PATIENTS WITH BREAST CANCER ON THE BASIS OF EXPRESSION OF SOMATIC-STEM TRANSITION GENES IN RESIDUAL TUMOR AFTER PRE-OPERATIVE TREATMENT | 2018 |
|
RU2682879C1 |
| METHOD FOR DIAGNOSING METASTASES OF COLON CANCER | 2016 |
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RU2647470C2 |
| DIAGNOSTIC TECHNIQUE FOR BREAST CANCER | 2012 |
|
RU2504785C1 |
