FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, in particular molecular biology and oncology. Method for predicting metastasis of ovarian cancer based on a group of microRNA genes by detecting methylation of at least three of five markers is described, the method is characterized in that the system markers are genes: miR-137, miR-193a, miR-1258, miR-203 and miR-127.
EFFECT: claimed method allows to detect ovarian cancer and to predict its metastasis with high clinical sensitivity and specificity.
1 cl, 2 dwg, 3 tbl, 3 ex
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Authors
Dates
2018-09-13—Published
2016-11-24—Filed