FIELD: anesthesiology and resuscitation.
SUBSTANCE: used to predict the risk of developing septic shock. DNA is isolated from peripheral venous blood and variants of the angiotensin II receptor AGTR1 gene are determined. If a patient has a TT variant of the AGTR1 gene (rs275651), the quantitative content of the peptide hormone angiotensin II in the blood plasma is determined. When the content of the peptide hormone angiotensin II is less than 200 pg/ml, the risk of developing septic shock is predicted.
EFFECT: early determination of whether a particular patient belongs to a risk group for the development of septic shock and the advisability of using angiotensin II preparations only for those patients whose predisposition to the development of shock is due to insufficient levels of the vasopressor hormone angiotensin II and the presence of the genetic variant TT rs275651 of its receptor - AGTR1.
1 cl, 1 dwg, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR DIAGNOSING EARLY MANIFESTATIONS OF BILIARY DYSKINESIA IN CHILDREN UNDER CONDITIONS OF BENZENE CONTAMINATION | 2024 |
|
RU2821553C1 |
| PREDICTION METHOD OF ARTERIAL HYPERTENSION COMORBIDE FORM AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE DEVELOPMENT | 2016 |
|
RU2620566C1 |
| METHOD FOR DIAGNOSING DISORDERS OF THE AUTONOMIC NERVOUS SYSTEM IN GIRLS OF PRESCHOOL AGE ASSOCIATED WITH EXCESSIVE CONTAMINATION OF BIOLOGICAL MEDIA IN CHILDREN WITH MANGANESE | 2021 |
|
RU2773830C1 |
| METHOD FOR PREDICTION OF RISK OF UNFAVOURABLE OUTCOME FOR PATIENTS IN CHRONIC CRITICAL CONDITION DUE TO CEREBRAL ACCIDENTS COMPLICATED BY PNEUMONIA | 2024 |
|
RU2822966C1 |
| METHOD FOR DETERMINING PREDISPOSITION TO DEVELOPING HYPERTENSIVE TYPE VEGETOVASCULAR DYSTONIA IN MALES, REALIZED BY EXCESSIVE CONTAMINATION WITH HEXANE | 2021 |
|
RU2766732C1 |
| METHOD OF GENETIC DIAGNOSTICS OF UNFAVOURABLE OUTCOME IN PATIENTS WITHIN ONE YEAR AFTER ACUTE CORONARY SYNDROME WITH ST SEGMENT ELEVATION | 2012 |
|
RU2502474C1 |
| DIAGNOSTIC TECHNIQUE FOR DEVELOPING PAINLESS MYOCARDIAL ISCHEMIA IN YOUNG FEMALES WITH ESTROGEN DEFICIENCY WITH ARTERIAL HYPERTENSION IN LATE FERTILE PERIOD DEPENDING ON INTERGENIC INTERACTIONS | 2015 |
|
RU2601381C1 |
| METHOD FOR PROGNOSIS OF SEVERITY OF DISSEMINATED BLOOD COAGULATION ACUTE SYNDROME USING INTRAVASCULAR GENETIC MONITORING | 2005 |
|
RU2303262C2 |
| DIAGNOSTIC TECHNIQUE FOR GENETIC PREDISPOSITION TO ISCHEMIC STROKE DEVELOPMENT IN PATIENTS WITH ATRIAL FIBRILLATION | 2015 |
|
RU2602451C1 |
| METHOD FOR PREDICTION OF UNFAVOURABLE OUTCOME OF HYPERTROPHIC CARDIOMYOPATHY | 2013 |
|
RU2527768C1 |
