FIELD: medicine; gynecology; medical genetics.
SUBSTANCE: invention can be used to predict the risk of developing endometriosis in women without a family history of endometriosis, being of Russian nationality, natives of the Central Black Earth Region of the Russian Federation. DNA from the peripheral venous blood is isolated. The polymorphic loci rs11031002 and rs11031005 of FSHB gene and rs117145500 of CHD9 gene are analyzed. If a combination of genotypes rs117145500 AA CHD9 is detected× rs11031002 TT FSHB× rs11031005 FSHB TTs a high risk of developing endometriosis is predicted.
EFFECT: method provides new criteria for assessing the risk of developing endometriosis in women without a family history of endometriosis, being of Russian nationality, who are natives of the Central Black Earth Region of the Russian Federation and are not related to each other, based on data on the combination of genotypes of FSHB and CHD9 genes.
1 cl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREDICTING RISK OF GRADE 3 MALIGNANCY OF TUMOR CELLS IN BREAST CANCER | 2024 |
|
RU2830352C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING LUMINAL SUBTYPE OF BREAST CANCER IN WOMEN | 2024 |
|
RU2828523C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING BREAST CANCER IN WOMEN WITHOUT OBESITY BY RESULTS OF GENETIC TESTING | 2024 |
|
RU2828525C1 |
| METHOD FOR PREDICTION OF INCREASED RISK OF DEVELOPING BREAST CANCER OF 3-4 STAGES OF DISEASE IN WOMEN | 2024 |
|
RU2830466C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING BREAST CANCER IN WOMEN WITH OBESITY BASED ON DATA ON POLYMORPHISM OF GENES JMJD1C, PPP1R21 AND PRMT6 | 2024 |
|
RU2830467C1 |
| METHOD OF PREDICTING RISK OF DEVELOPING BREAST CANCER IN WOMEN USING MOLECULAR GENETIC DATA | 2023 |
|
RU2809798C1 |
| METHOD FOR PREDICTION OF RISK OF GENITAL ENDOMETRIOSIS | 2017 |
|
RU2650994C1 |
| METHOD FOR FORECASTING THE RISK OF DEVELOPMENT OF COMBINATION OF GENITAL ENDOMETRIOSIS AND HYPERPLASTIC ENDOMETRY PROCESSES BASED ON MOLECULAR-GENETIC DATA | 2018 |
|
RU2679637C1 |
| METHOD FOR PREDICTING THE RISK OF DEVELOPING DEEP INFILTRATIVE ENDOMETRIOSIS IN WOMEN OF REPRODUCTIVE AGE | 2022 |
|
RU2775544C1 |
| METHOD FOR PREDICTION OF RISK OF DEVELOPING TRIPLE NEGATIVE BREAST CANCER IN WOMEN USING MOLECULAR GENETIC DATA | 2024 |
|
RU2830346C1 |
