FIELD: pharmaceuticals.
SUBSTANCE: group of inventions relates to methods of producing 6-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide (Compound I). The methods are performed according to the steps, conditions and intermediate products specified in the claims.
EFFECT: improved methods of producing Compound I for large-scale production, ensuring high yield and purity of the product.
5 cl, 6 ex
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Authors
Dates
2023-12-25—Published
2020-02-24—Filed