FIELD: biotechnology.
SUBSTANCE: following is described: a test system for determining the biological activity of artificial agonists of the human thrombopoietin receptor, including cells of the 32D clone 3 line transformed with a vector containing a nucleotide sequence encoding the human thrombopoietin receptor.
EFFECT: possibility of using this test system to determine the biological activity and immunogenicity of artificial human thrombopoietin receptor agonists in the development of new medicinal products.
9 cl, 3 dwg, 2 tbl, 3 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD OF INDUSTRIAL PURIFICATION OF ROMIPLOSTIM | 2021 |
|
RU2804622C2 |
ISOLATED NUCLEIC ACID MOLECULE ENCODING CHIMERIC TIE-2-LIGAND (VARIANTS), CHIMERIC OR MODIFIED TIE-2-LIGAND AND METHOD FOR ITS PREPARING, VECTOR, METHOD FOR PREPARING SYSTEM VECTOR-HOST, CONJUGATE, PHARMACEUTICAL COMPOSITION | 1997 |
|
RU2233880C2 |
NEW CYTOKINE ZALPHA 11-LIGAND | 2000 |
|
RU2258710C2 |
NEW LIGAND OF CYTOKINE RECEPTOR ZCYTOR17 | 2003 |
|
RU2490276C2 |
DISEASE DIAGNOSTICS TECHNIQUE BY ORGANISM TISSUES, BLOOD OR LIQUIDS SCREENING IN ANIMAL OR HUMAN FOR NONPHYSIOLOGICAL HEPSIDIN LEVELS AND ITS THERAPEUTIC APPLICATION | 2003 |
|
RU2359268C2 |
LIVER ORGANOID, VERSIONS OF USE THEREOF AND CULTURE METHOD FOR PRODUCTION THEREOF | 2011 |
|
RU2579995C2 |
METHOD FOR DETECTING LEPTIN RECEPTOR LIGANDS | 2003 |
|
RU2373534C2 |
METHOD FOR INHIBITION OF HEPATOCYTE PROLIFERATION, METHOD FOR INHIBITION OF HEPATOCYTE CELL ADHESION AND METHOD FOR INHIBITION OF BIOLOGICAL ACTIVITY ANGPTL4 IN HEPATOCYTES OR HEPATOCYTE PRECURSORS | 2005 |
|
RU2380411C2 |
METHOD FOR GM-CSFRα INHIBITION IN PATIENT | 2012 |
|
RU2639546C2 |
METHOD FOR PROPHYLAXIS AND TREATMENT OF ESTROGEN-DEPENDENT DISEASES AND DISORDERS | 1998 |
|
RU2214236C2 |
Authors
Dates
2023-12-27—Published
2023-02-13—Filed