TEST SYSTEM AND METHODS OF DETERMINING BIOLOGICAL ACTIVITY OF HUMAN THROMBOPOETIN RECEPTOR AGONISTS Russian patent published in 2023 - IPC G01N33/50 C12N15/09 C12N15/63 C12N15/85 

Abstract RU 2810503 C1

FIELD: biotechnology.

SUBSTANCE: following is described: a test system for determining the biological activity of artificial agonists of the human thrombopoietin receptor, including cells of the 32D clone 3 line transformed with a vector containing a nucleotide sequence encoding the human thrombopoietin receptor.

EFFECT: possibility of using this test system to determine the biological activity and immunogenicity of artificial human thrombopoietin receptor agonists in the development of new medicinal products.

9 cl, 3 dwg, 2 tbl, 3 ex

Similar patents RU2810503C1

Title Year Author Number
METHOD OF INDUSTRIAL PURIFICATION OF ROMIPLOSTIM 2021
  • Ershov Aleksandr Viktorovich
  • Ershova Olga Anatolevna
  • Anisimov Roman Lvovich
  • Katorkin Sergej Aleksandrovich
RU2804622C2
ISOLATED NUCLEIC ACID MOLECULE ENCODING CHIMERIC TIE-2-LIGAND (VARIANTS), CHIMERIC OR MODIFIED TIE-2-LIGAND AND METHOD FOR ITS PREPARING, VECTOR, METHOD FOR PREPARING SYSTEM VECTOR-HOST, CONJUGATE, PHARMACEUTICAL COMPOSITION 1997
  • Dehvis Sehmjuel'
  • Jankopoulos Dzhordzh D.
RU2233880C2
NEW CYTOKINE ZALPHA 11-LIGAND 2000
  • Novak Dzhulija Eh.
  • Presnell Skott R.
  • Spreker Sindi A.
  • Foster Donald K.
  • Kholli Richard D.
  • Gross Dzhejn A.
  • Dzhonston Dzhehnet V.
  • Nelson Ehndrju Dzh.
  • Dillon Stejsi R.
  • Khehmmond Andzhela K.
RU2258710C2
NEW LIGAND OF CYTOKINE RECEPTOR ZCYTOR17 2003
  • Spresher Sindi A.
  • Kejper Jozef L.
  • Dasovich Marija M.
  • Grant Frehnsis Dzh.
  • Khehmmond Andzhela K.
  • Novak Dzhulija E.
  • Gross Dzhejn A.
  • Dillon Stejsi R.
RU2490276C2
DISEASE DIAGNOSTICS TECHNIQUE BY ORGANISM TISSUES, BLOOD OR LIQUIDS SCREENING IN ANIMAL OR HUMAN FOR NONPHYSIOLOGICAL HEPSIDIN LEVELS AND ITS THERAPEUTIC APPLICATION 2003
  • Kulaksiz Khasan
  • Geatsintov Kiril E.
  • Janetsko Al'Fred
  • Shtremmel' Vol'Fgang
RU2359268C2
LIVER ORGANOID, VERSIONS OF USE THEREOF AND CULTURE METHOD FOR PRODUCTION THEREOF 2011
  • Uch Ortega Meritksel
  • Klevers Jokhannes Karolus
RU2579995C2
METHOD FOR DETECTING LEPTIN RECEPTOR LIGANDS 2003
  • Jokkers Ral'F
  • Kutjur'E Siril
RU2373534C2
METHOD FOR INHIBITION OF HEPATOCYTE PROLIFERATION, METHOD FOR INHIBITION OF HEPATOCYTE CELL ADHESION AND METHOD FOR INHIBITION OF BIOLOGICAL ACTIVITY ANGPTL4 IN HEPATOCYTES OR HEPATOCYTE PRECURSORS 2005
  • Banting Stjuart
  • Gerber Khans-Peter
  • Ljan Sjao Khuan
RU2380411C2
METHOD FOR GM-CSFRα INHIBITION IN PATIENT 2012
  • Kokhen Emma Syuzan
  • Minter Ralf Rajmond
  • Kharrison Paula Rosamund
  • Sliman Metyu Aleksandr
  • Nesh Endryu Donald
  • Fabri Lyuis Dzherri
RU2639546C2
METHOD FOR PROPHYLAXIS AND TREATMENT OF ESTROGEN-DEPENDENT DISEASES AND DISORDERS 1998
  • Makdonnell Donal'D P.
  • Norris Dzhon
  • Konnor Kehrolajn
  • Vidzhajaratne Ashini
RU2214236C2

RU 2 810 503 C1

Authors

Saparova Valeriya Byashimovna

Afanasyeva Alina Nikolaevna

Shitikova Viktoriya Olegovna

Makarenko Igor Evgenevich

Dates

2023-12-27Published

2023-02-13Filed