FIELD: biotechnology.
SUBSTANCE: invention relates to a ribonucleoprotein complex for genomic editing of alleles of exon 2 of the BOLA-DRB3 gene susceptible to bovine leukemia virus, including the CAS 9 protein and gRNA characterized by 5´-GACCGAGCGGGUGCGGUACCUGG-3.
EFFECT: invention is effective for genomic editing for the reproduction of high-value breeding dairy cattle resistant to the bovine leukemia virus.
1 cl, 2 dwg, 1 tbl
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