FIELD: pharmaceuticals.
SUBSTANCE: this disclosure relates to pharmaceutical compositions containing Compound 1 and/or tautomers thereof, or a pharmaceutically acceptable salt or hydrate thereof. Pharmaceutical compositions may contain microcrystalline cellulose, for example, silicated microcrystalline cellulose, as a compressible filler. Pharmaceutical compositions can be prepared by a process involving a dry granulation process. Pharmaceutical compositions may contain a weight ratio of Compound 1 drug substance to intragranular compressible excipient greater than 1:1.
Compound 1
EFFECT: obtaining pharmaceutical compositions with CDC7 inhibitor.
7 cl, 2 dwg, 11 tbl, 4 ex
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