PYRUVATE CARBOXYLASE GENE PROMOTER MUTANT AND ITS APPLICATION Russian patent published in 2024 - IPC C12N15/113 C12N15/67 C12N15/77 C12P13/04 

Abstract RU 2812048 C1

FIELD: biotechnology.

SUBSTANCE: invention is a mutant of the promoter of the pyruvate carboxylase gene of Corynebacterium glutamicum. This mutant has improved promoter activity compared to the wild type promoter and can be used to increase the expression of the target gene.

EFFECT: functional ligation of the specified mutant with the pyruvate carboxylase gene increases the intensity of pyruvate carboxylase expression, thereby improving the efficiency of amino acid production by the strain.

21 cl, 2 dwg, 6 tbl, 4 ex

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RU 2 812 048 C1

Authors

Sun Jibin

Liu Jiao

Zheng Ping

Shi Tuo

Zhou Wenjuan

Chen Jiuzhou

Guo Xuan

Ma Yanhe

Dates

2024-01-22Published

2021-07-13Filed