MIXTURE OF 3-{(2E/Z)-2-[3-(HYDROXYMINO)-4-OXO-4-P-TOLYLBUTAN-2-YLIDENE]HYDRAZINYL}-QUINOXALIN-2(1H)-ONE ISOMERS Russian patent published in 2024 - IPC C07D241/44 A61K31/498 

Abstract RU 2814666 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to the use of a mixture of isomers 3-{(2E/Z)-2-[3-(hydroxymino)-4-oxo-4-para-tolylbutan-2-ylidene]hydrazinyl}-quinoxalin-2(1H)-one described by formula 1 as an agent having an antioxidant effect.

EFFECT: following is proposed: the use of a mixture of isomers 3-{(2E/Z)-2-[3-(hydroxymino)-4-oxo-4-para-tolylbutan-2-ylidene]hydrazinyl}-quinoxalin-2(1H)-one described by formula 1, as a agent with pronounced antioxidant activity in the model of Fe2+-induced lipid peroxidation, which can be used to obtain new agents of antioxidant action.

1 cl, 1 tbl, 2 ex

Similar patents RU2814666C1

Title Year Author Number
METHOD FOR PRODUCTION OF (Z)-ETHYL 2-(4-(4-CHLOROPHENYL)-2,4-DIOXO-3-(3-OXO-3,4-DIHYDROQUINOXALINE-2(1H)-YLIDENE)BUTANAMIDO)-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE 2017
  • Dmitriev Maksim Viktorovich
  • Stepanova Ekaterina Evgenevna
  • Chervyakov Artem Valentinovich
  • Mashevskaya Irina Vladimirovna
RU2644944C1
2-[6-METHYL-4-(TIETANE-3-YLOXY)PYRIMIDINE-2-YLTHIO] ACETIC ACID METHYLIDENHYDRAZIDE WITH ANTIOXIDANT ACTIVITY 2016
  • Kataev Valerij Alekseevich
  • Meshcheryakova Svetlana Alekseevna
  • Shumadalova Alina Viktorovna
  • Farkhutdinov Rafagat Ravilevich
  • Petrova Irina Vladimirovna
  • Kataev Valentin Valerevich
RU2626651C1
3-AROYL-2-(2-ARYLHYDRAZONO)PYRROLO [1,2-a] QUINOXALINE,4-(2H,5H)DIONES POSSESSING ANALGESIC ACTIVITY 2011
  • Mashevskaja Irina Vladimirovna
  • Kislina Lalita Viktorovna
  • Makhmudov Ramiz Ragibovich
  • Maslivets Andrej Nikolaevich
RU2471798C1
METHOD OF PRODUCING 6-ARYL-4-AMINOPICOLINATES 2010
  • Renga Dzhejms
  • Uajteker Gregori
  • Arndt Kim
  • Lou Kristian
RU2525918C2
METHOD OF PRODUCING 3-DIHALOMETHYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES 2007
  • Patsenok Sergij
  • Norbert Lui
  • Neeff Arnd
RU2470015C2
(Z)-ETHYL2-(4-(4-CHLOROPHENYL)-2,4-DIOXO-3-(3-OXO-3,4-DIHYDROQUINOXALIN-2(1H)-YLIDENE)BUTANAMIDO)-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE HAVING ANTIDIABETIC ACTIVITY, AND METHOD FOR PRODUCTION THEREOF 2015
  • Pchelintseva Darya Igorevna
  • Kotegov Viktor Petrovich
  • Pavlov Petr Timofeevich
  • Mashevskaya Irina Vladimirovna
  • Makhmudov Ramiz Ragibovich
RU2606230C1
N-BUTYL-2-[6-METHYL-4-(THIETAN-3-YLOXY)PYRIMIDIN-2-YLTHIO]ACETAMIDE EXHIBITING ANTIOXIDANT ACTIVITY 2024
  • Meshcheriakova Svetlana Alekseevna
  • Vinogradova Iuliia Igorevna
  • Samorodov Aleksandr Vladimirovich
  • Shumadalova Alina Viktorovna
  • Valiullina Zulfiia Albertovna
RU2824634C1
DERIVATIVES OF 3-SUBSTITUTED 4-ARYLQUINOLIN-2-ONE AS MODULATORS OF POTASSIUM CHANNEL 1999
  • Khevavasam Pijazena
  • Starrett Dzhon E. Ml.
RU2240998C2
METHOD OF PRODUCING 4-ARYL-2-OXO-2H-CHROMENE-3-CARBONITRILES 2015
  • Bardasov Ivan Nikolaevich
  • Alekseeva Anastasija Jurevna
  • Ershov Oleg Vjacheslavovich
  • Nasakin Oleg Evgenevich
RU2577524C1
16-{2-BENZOYLAMINO-2-[(3,5-DI-TRET-BUTHYL-4-HYDROXUPHENYL)ALKYL-CARBAMOYL]VINYL}-LABDATRIENS WITH ANTIOXIDANT, HEPATOPROTECTION AND HEMOSTIMULATING EFFECT 2007
  • Kharitonov Jurij Viktorovich
  • Shul'Ts Ehl'Vira Ehduardovna
  • Sorokina Irina Vasil'Evna
  • Tolstikova Tat'Jana Genrikhovna
  • Baev Dmitrij Sergeevich
  • Zhukova Natal'Ja Anatol'Evna
  • Tolstikov Genrikh Aleksandrovich
RU2346940C1

RU 2 814 666 C1

Authors

Bobrov Pavel Sergeevich

Anenko Denis Stanislavovich

Abisalova Irina Leonidovna

Suboch Georgii Anatolevich

Aksenov Aleksandr Viktorovich

Sergeeva Elena Olegovna

Glizhova Tamara Nikolaevna

Dates

2024-03-04Published

2023-03-01Filed