FIELD: chemical industry.
SUBSTANCE: present invention relates to the use of (5Z)-2-amino-5-bromo-5-(1-bromo-2-oxo-2-phenylethylidene)-4-oxo-1H-4,5-dihydrofuran-3-carboxylic acid nitrile as an antifungal agent
.
EFFECT: application of the compound as an antifungal agent with a minimum inhibitory concentration of 1.0 mcg/ml against Candida albicans NCTC 885-653, 0.5 mcg/ml against Candida tropicalis RKPGY-1513/784, 0.5 mcg/ml against Candida krusei RKPGY-1472/310, 1.0 mcg/ml against Candida glabrata RKPGY-1485/47.
1 cl, 1 tbl
| Title |
Year |
Author |
Number |
| APPLICATION OF 2-AMINO-5-BROMO-5-(1-BROM-2-OXO-2-PHENYLETHYLIDENE)-4-OXO-1Н-4,5-DIHYDROFURAN-3-CARBOXIC ACID ETHYL AS A MEDICINE WITH TUBERCULOSTATIC ACTIVITY |
2023 |
- Ivanov Dmitrii Vladimirovich
- Igidov Nazim Musabekovich
- Novikova Valentina Vasilevna
|
RU2803601C1 |
| USE OF (5Z)-2-AMINO-5-(1-BROM-2-OXO-2-PHENYLETHYLIDENE)-4-OXO-1H-4,5-DIHYDROFURAN-3-CARBOXIC ACID ETHER AS A MEDICINAL AGENT WITH TUBERCULOSTATIC ACTIVITY |
2022 |
- Ivanov Dmitrii Vladimirovich
- Igidov Nazim Musabekovich
- Balandina Svetlana Iurevna
|
RU2799759C1 |
| ETHYL ALCOHOL (5Z)-2-AMINO-5-[1-BROMO-2-(4-BROMOPHENYL)-2-OXO-ETHYLIDENE]-4-OXO-1H-4,5-DIHYDROFURAN-3-CARBOXYLIC ACID ETHYL ESTER, SHOWING ANTIFUNGAL ACTIVITY |
2018 |
- Ivanov Dmitrij Vladimirovich
- Makhmudov Ramiz Ragibovich
- Igidov Nazim Musabekovich
- Novikova Valentina Vasilevna
|
RU2654207C1 |
| BENZYLAMMONIUM SALT OF 4-ETHOXYCARBONYL-5-OXO-2-(2-OXO-2-PHENYLETHYLIDENE)-2,5-DIHYDRO-1H-PYRROLE-3-OLATE, SHOWING ANTIMICROBIAL ACTIVITY |
2022 |
- Ivanov Dmitrii Vladimirovich
- Igidov Nazim Musabekovich
- Balandina Svetlana Iurenva
|
RU2781135C1 |
| USE OF SUBSTITUTED ESTERS OF (Z)-2-(2-(DIPHENYLMETHYLENE)HYDRAZINYL)-5,5-DIMETHYL-4-OXOHEX-2-ENOIC ACID AS AN ANTIBACTERIAL AND ANTIFUNGAL AGENT |
2021 |
- Syutkina Alena Ivanovna
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Sergej Aleksandrovich
|
RU2768761C1 |
| APPLICATION OF THE SILVER SALT OF N-{4-[(1,3-THIAZOLE-2-YL)SULPHAMOYL]PHENYL}-1-PHENYL-5-(4-ETHOXYPHENYL)PYRAZOLE-3-CARBOXAMIDE AS AN ANTIFUNGAL AGENT AGAINST STRAINS OF C. TROPICALIS, C. KRUSEI, AND C. GLABRATA FUNGI |
2020 |
- Gejn Vladimir Leonidovich
- Bobrovskaya Olga Vasilevna
- Russkikh Aleksandr Alekseevich
- Novikova Valentina Vasilevna
- Makhmudov Ramiz Ragibovich
|
RU2763724C1 |
| APPLICATION OF ANTIFUNGAL AGENT BASED ON 2-((4-R1-5-R2-3-(ETHOXYCARBONYL)THIOPHENE-2-IL)AMINO)-4-OXO-4-R3-BUT-2-ENO ACIDS IN RELATION TO CANDIDA ALDICANS |
2021 |
- Shipilovskikh Sergej Aleksandrovich
- Rubtsov Aleksandr Evgenevich
- Makhmudov Ramiz Ragibovich
- Shipilovskikh Darya Aleksandrovna
- Tkachenko Aleksandr Georgievich
- Nesterova Larisa Yurevna
|
RU2770598C1 |
| 2-AMINO-1-BENZAMIDO-5-[2-(NAPHTHALENE-1-YL)-2-OXOETHYLIDENE]-4-OXO-4,5-DIHYDRO-1H-PYRROLE-3-CARBOXAMIDE EXHIBITING CYTOTOXIC AND PROAPOPTOGENIC PROPERTIES AGAINST HUMAN SOLID TUMOUR CELLS, INCLUDING THOSE RESISTANT TO CHEMOTHERAPEUTIC AGENTS |
2020 |
- Bojchuk Sergej Vasilevich
- Igidov Nazim Musabekovich
- Zykova Svetlana Sergeevna
- Galembikova Ajgul Rafikovna
- Aukhadieva Aida Maratovna
- Bikinieva Firyuza Fanisovna
- Nurgatina Ilmira Ilyazovna
- Gankova Kseniya Leonidovna
- Shustov Maksim Vadimovich
|
RU2753479C1 |
| ETHYL ETHER 2-AMINO-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)-5-(2-(4-ETHYLPHENYL)-2-OXOETHYLIDENE)-4-OXO- 4,5-DIHYDRO-1H-PYRROL-3-CARBOXYLIC ACID WITH ANALGESIC ACTIVITY |
2023 |
- Shipilovskikh Sergei Aleksandrovich
- Makhmudov Ramiz Ragibovich
- Lipin Dmitrii Vladimirovich
- Parkhoma Kseniia Iurevna
|
RU2810070C1 |
| ETHYL ETHERS OF 2-AMINO-1-BENZOYLAMINO-4-OXO-5-(2-OXO-2-ARYL-ETHYLIDENE)-4,5-DIHYDRO-1H-PYRROLIDINE-3-CARBOXYLIC ACIDS, HAVING ANTI-TUMOUR ACTIVITY AND METHOD FOR PRODUCTION THEREOF |
2015 |
- Bojchuk Sergej Vasilevich
- Zykova Svetlana Sergeevna
- Galembikova Ajgul Rafikovna
- Ramazanov Bulat Rashitovich
- Igidov Nazim Musabekovich
- Odegova Tatyana Fedorovna
- Kiselev Maksim Aleksandrovich
- Semina Irina Ivanovna
|
RU2607920C2 |
