APPLICATION OF 2-AMINO-5-BROMO-5-(1-BROM-2-OXO-2-PHENYLETHYLIDENE)-4-OXO-1Н-4,5-DIHYDROFURAN-3-CARBOXIC ACID ETHYL AS A MEDICINE WITH TUBERCULOSTATIC ACTIVITY Russian patent published in 2023 - IPC A61K31/341 A61P31/06 

Abstract RU 2803601 C1

FIELD: organic chemistry.

SUBSTANCE: derivatives of 2-aminofuran, namely biologically active substances - ethyl ester 2-amino-5-bromo-5-(1-bromo-2-oxo-2-phenylethylidene)-4-oxo- 1H-4,5-dihydrofuran-3-carboxylic acid of Formula 1, which can be used as an antimicrobial drug. The application of 2-amino-5-bromo-5-(1-bromo-2-oxo-2-phenylethylidene)-4-oxo- 1H -4,5-dihydrofuran-3-carboxylic acid ethyl ester as a drug is presented, with tuberculostatic activity.

EFFECT: 2-amino-5-bromo-5-(1-bromo-2-oxo-2-phenylethylidene)-4-oxo-1H-4,5-dihydrofuran-3-carboxylic acid ethyl ester of formula 1 having antimicrobial action.

1 cl, 1 tbl

Similar patents RU2803601C1

Title Year Author Number
USE OF (5Z)-2-AMINO-5-(1-BROM-2-OXO-2-PHENYLETHYLIDENE)-4-OXO-1H-4,5-DIHYDROFURAN-3-CARBOXIC ACID ETHER AS A MEDICINAL AGENT WITH TUBERCULOSTATIC ACTIVITY 2022
  • Ivanov Dmitrii Vladimirovich
  • Igidov Nazim Musabekovich
  • Balandina Svetlana Iurevna
RU2799759C1
USE OF (5Z)-2-AMINO-5-BROMO-5-(1-BROMO-2-OXO-2-PHENYLETHYLIDENE)-4-OXO-1N-4,5-DIHYDROFURAN-3-CARBOXYLIC ACID NITRILE AS AN AGENT, SHOWING ANTIFUNGAL ACTIVITY 2021
  • Ivanov Dmitrij Vladimirovich
  • Igidov Nazim Musabekovich
  • Novikova Valentina Vasilevna
  • Makhmudov Ramiz Ragibovich
RU2815046C2
ETHYL ALCOHOL (5Z)-2-AMINO-5-[1-BROMO-2-(4-BROMOPHENYL)-2-OXO-ETHYLIDENE]-4-OXO-1H-4,5-DIHYDROFURAN-3-CARBOXYLIC ACID ETHYL ESTER, SHOWING ANTIFUNGAL ACTIVITY 2018
  • Ivanov Dmitrij Vladimirovich
  • Makhmudov Ramiz Ragibovich
  • Igidov Nazim Musabekovich
  • Novikova Valentina Vasilevna
RU2654207C1
BENZYLAMMONIUM SALT OF 4-ETHOXYCARBONYL-5-OXO-2-(2-OXO-2-PHENYLETHYLIDENE)-2,5-DIHYDRO-1H-PYRROLE-3-OLATE, SHOWING ANTIMICROBIAL ACTIVITY 2022
  • Ivanov Dmitrii Vladimirovich
  • Igidov Nazim Musabekovich
  • Balandina Svetlana Iurenva
RU2781135C1
ETHYL ETHERS OF 2-AMINO-1-BENZOYLAMINO-4-OXO-5-(2-OXO-2-ARYL-ETHYLIDENE)-4,5-DIHYDRO-1H-PYRROLIDINE-3-CARBOXYLIC ACIDS, HAVING ANTI-TUMOUR ACTIVITY AND METHOD FOR PRODUCTION THEREOF 2015
  • Bojchuk Sergej Vasilevich
  • Zykova Svetlana Sergeevna
  • Galembikova Ajgul Rafikovna
  • Ramazanov Bulat Rashitovich
  • Igidov Nazim Musabekovich
  • Odegova Tatyana Fedorovna
  • Kiselev Maksim Aleksandrovich
  • Semina Irina Ivanovna
RU2607920C2
2-AMINO-1-BENZAMIDO-5-[2-(NAPHTHALENE-1-YL)-2-OXOETHYLIDENE]-4-OXO-4,5-DIHYDRO-1H-PYRROLE-3-CARBOXAMIDE EXHIBITING CYTOTOXIC AND PROAPOPTOGENIC PROPERTIES AGAINST HUMAN SOLID TUMOUR CELLS, INCLUDING THOSE RESISTANT TO CHEMOTHERAPEUTIC AGENTS 2020
  • Bojchuk Sergej Vasilevich
  • Igidov Nazim Musabekovich
  • Zykova Svetlana Sergeevna
  • Galembikova Ajgul Rafikovna
  • Aukhadieva Aida Maratovna
  • Bikinieva Firyuza Fanisovna
  • Nurgatina Ilmira Ilyazovna
  • Gankova Kseniya Leonidovna
  • Shustov Maksim Vadimovich
RU2753479C1
ETHYL ETHER 2-AMINO-(3-CYANO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-YL)-5-(2-(4-ETHYLPHENYL)-2-OXOETHYLIDENE)-4-OXO- 4,5-DIHYDRO-1H-PYRROL-3-CARBOXYLIC ACID WITH ANALGESIC ACTIVITY 2023
  • Shipilovskikh Sergei Aleksandrovich
  • Makhmudov Ramiz Ragibovich
  • Lipin Dmitrii Vladimirovich
  • Parkhoma Kseniia Iurevna
RU2810070C1
APPLICATION OF ANTIFUNGAL AGENT BASED ON 2-((4-R1-5-R2-3-(ETHOXYCARBONYL)THIOPHENE-2-IL)AMINO)-4-OXO-4-R3-BUT-2-ENO ACIDS IN RELATION TO CANDIDA ALDICANS 2021
  • Shipilovskikh Sergej Aleksandrovich
  • Rubtsov Aleksandr Evgenevich
  • Makhmudov Ramiz Ragibovich
  • Shipilovskikh Darya Aleksandrovna
  • Tkachenko Aleksandr Georgievich
  • Nesterova Larisa Yurevna
RU2770598C1
ETHYL ETHER (5 E)-2-AMINO-5-[2-(4-METHYLPHENYL)-2-HYDROXYETHYLIDENE]-1-(3-NITROPHENYL)-4-OXO-1H-4,5-DIHYDROPYRROL-3-CARBOXYLIC ACID, WITH ANTINOCICEPTIVE ACTIVITY 2021
  • Rubtsov Aleksandr Evgenevich
  • Makhmudov Ramiz Ragibovich
RU2771031C1
SUBSTITUTED ETHYL ESTERS (E)-2-(5-AMINO-4-R1-3-OXO-2-(2-OXO-2-(P-TOLYL)ETHYLIDENE)-2,3-DIHYDRO-1H-PYRROL- 1-YL)-5,6,7,8-TETRAHYDRO-4H-CYCLOHEPTA[b]THIOPHENE-3-CARBOXYLIC ACID, WHICH HAS ANTICANCER ACTIVITY IN THE TREATMENT OF LUNG MELANOMA 2023
  • Shipilovskikh Sergei Aleksandrovich
  • Timin Aleksandr Sergeevich
RU2806324C1

RU 2 803 601 C1

Authors

Ivanov Dmitrii Vladimirovich

Igidov Nazim Musabekovich

Novikova Valentina Vasilevna

Dates

2023-09-18Published

2023-03-29Filed