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2 816 397

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IPC

C07D311/86(2006-01-01)

A61K31/352(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2023105547, 2023-03-09

(24)

Start date

2023-03-09

(22)

Actual filing date

2023-03-09

(45)

Published

2024-03-28

(72)

Inventor

Chernov Nikita MaksimovichLukyanenko Vladislav IgorevichShutov Roman VadimovichAnaneva Elena PetrovnaYakovlev Igor Pavlovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Khimiko-Farmatsevticheskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii Vo Spkhfu Minzdrava Rossii)

4,4-DIMETHYL-9-OXO-4,4A-DIHYDRO-9H-XANTHENE-2-CARBONITRILES AND METHOD OF THEIR PREPARATION Russian patent published in 2024 - IPC C07D311/86 A61K31/352 A61P31/04

Abstract RU 2816397 C1

FIELD: organic; medicinal chemistry.

SUBSTANCE: invention relates to the use of 4,4-dimethyl-9-oxo-4,4a-dihydro-9H-xanthene-2-carbonitriles of formula I, where R¹=Н, R²=Cl, R³=Н (Ia), R¹=Н, R²=Br, R³=Н (Ib), R¹=Н, R²=F, R³=Н (Ic), R¹=Н, R²=Н, R³=Н (Id), R¹=Н, R²=СН₃, R³=Н (Ie), R¹=Н, R²=CH₃O, R³=Н (If), R¹=Н, R²=СН₃, R³=СН₃ (Ig), R¹, R²=benzo, R³=Н (Ih), as an antimicrobial agent against Staphylococcus aureus.

EFFECT: obtaining a number of polyfunctional heterocyclic compounds of formula Ia-h, which have antimicrobial activity.

1 cl, 1 tbl, 1 ex

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RU 2 816 397 C1

Authors

Chernov Nikita Maksimovich

Lukyanenko Vladislav Igorevich

Shutov Roman Vadimovich

Ananeva Elena Petrovna

Yakovlev Igor Pavlovich

Dates

2024-03-28—Published

2023-03-09—Filed