FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to creation of a cryoprotective solution for blood storage. Cryoprotectant for freezing whole blood at sub-moderately low -20 °C and moderately low -40 °C temperatures includes glycerol, sodium chloride, sodium phosphate disubstituted, water for injections and additionally dimethyl sulphoxide and lactulose at the following ratio of ingredients, vol.%: glycerol 20, dimethyl sulphoxide 10, lactulose 2.5, sodium chloride 0.25; sodium phosphate disubstituted 0.25; water for injections up to 100%.
EFFECT: disclosed whole blood cryoprotectant provides preservation of morphofunctional integrity of blood cells in conditions of submoderate and moderately low temperatures.
1 cl, 5 ex
| Title | Year | Author | Number | 
|---|---|---|---|
| WHOLE BLOOD CRYOPROTECTOR FOR LOW-TEMPERATURE FREEZING | 2024 | 
 | RU2837538C1 | 
| COLD-SAFETY SOLUTION FOR FREEZING LEUKOCYTES AT SUB-MODERATE TEMPERATURE | 2002 | 
 | RU2240000C2 | 
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 | RU2290808C2 | 
| SOLUTION FOR CELL SUSPENSIONS PRESERVATION | 2015 | 
 | RU2621295C2 | 
| CRYOPROTECTIVE SOLUTION FOR MODERATELY HYPOTHERMIC LEUKOCYTE PRESERVATION (-40°C) | 2009 | 
 | RU2439877C2 | 
| CRYOCONSERVING AGENT FOR LEUCOCYTES | 2006 | 
 | RU2301524C1 | 
| FROST PROTECTION SOLUTION FOR NUCLEAR BLOOD CELL FREEZING | 2011 | 
 | RU2464991C1 | 
| PROTECTIVE SOLUTION FOR PRESERVING LEUKOCYTE AT TEMPERATURE -10°C | 2004 | 
 | RU2261595C1 | 
| SOLUTION FOR LEUKOCYTE PRESERVATION AT NEAR-ZERO TEMPERATURE | 2006 | 
 | RU2311027C1 | 
| COMBINED CRYOPROTECTIVE SOLUTION FOR THROMBOCYTE FREEZING | 2012 | 
 | RU2477953C1 | 
Authors
Dates
2024-03-29—Published
2023-10-20—Filed