FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to creation of a cryoprotective solution for blood storage. Cryoprotectant for freezing whole blood at sub-moderately low -20 °C and moderately low -40 °C temperatures includes glycerol, sodium chloride, sodium phosphate disubstituted, water for injections and additionally dimethyl sulphoxide and lactulose at the following ratio of ingredients, vol.%: glycerol 20, dimethyl sulphoxide 10, lactulose 2.5, sodium chloride 0.25; sodium phosphate disubstituted 0.25; water for injections up to 100%.
EFFECT: disclosed whole blood cryoprotectant provides preservation of morphofunctional integrity of blood cells in conditions of submoderate and moderately low temperatures.
1 cl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| CRYOPROTECTIVE SOLUTION FOR LEUKOCYTE FREEZING AT LOW TEMPERATURE | 2004 |
|
RU2290808C2 |
| COLD-SAFETY SOLUTION FOR FREEZING LEUKOCYTES AT SUB-MODERATE TEMPERATURE | 2002 |
|
RU2240000C2 |
| CRYOPROTECTIVE SOLUTION FOR MODERATELY HYPOTHERMIC LEUKOCYTE PRESERVATION (-40°C) | 2009 |
|
RU2439877C2 |
| CRYOCONSERVING AGENT FOR LEUCOCYTES | 2006 |
|
RU2301524C1 |
| SOLUTION FOR CELL SUSPENSIONS PRESERVATION | 2015 |
|
RU2621295C2 |
| SOLUTION FOR LEUKOCYTE PRESERVATION AT NEAR-ZERO TEMPERATURE | 2006 |
|
RU2311027C1 |
| PROTECTIVE SOLUTION FOR PRESERVING LEUKOCYTE AT TEMPERATURE -10°C | 2004 |
|
RU2261595C1 |
| COMBINED CRYOPROTECTIVE SOLUTION FOR THROMBOCYTE FREEZING | 2012 |
|
RU2477953C1 |
| CRYOPROTECTIVE SOLUTION TO FREEZE LEUCOCYTES AT MODERATE-LOW TEMPERATURE | 2001 |
|
RU2184449C1 |
| SOLUTION FOR PRESERVATION OF BONE MARROW OF MAMMALS AT LOW TEMPERATURES | 1990 |
|
RU1772911C |
