MICROORGANISM HAVING ENHANCED ABILITY TO PRODUCE L-AMINO ACID WITH BRANCHED CHAIN, AND METHOD OF PRODUCING L-AMINO ACID WITH BRANCHED CHAIN USING SAME Russian patent published in 2024 - IPC C07K14/195 C12N15/77 C12P13/06 C12P13/08 

FIELD: biotechnology.

SUBSTANCE: disclosed is a polynucleotide having promoter activity and containing a nucleotide substitution with another nucleotide in at least two or more corresponding positions selected from positions 34, 36, 37, 41 and 43 of the nucleotide sequence presented in SEQ ID NO: 1. Said polynucleotide comprises 34^th nucleotide substitution with T; replacement of 36^th nucleotide with T; replacing 37^th nucleotide with G; substitution of 41^st nucleotide with T; replacement of 43^rd nucleotide with A or a combination thereof in the nucleotide sequence presented in SEQ ID NO: 1. Also disclosed are a microorganism producing a branched L-amino acid, containing said polynucleotide, and a method of producing a branched L-amino acid using said microorganism.

EFFECT: invention enables to obtain a branched-chain L-amino acid with increased output.

8 cl, 10 tbl, 5 ex