METHOD FOR ASSESSING RESISTANCE OF SQUAMOUS CELL CANCER OF THROAT TO RADIATION THERAPY AND SET OF TESTS FOR IMPLEMENTATION THEREOF Russian patent published in 2024 - IPC C12Q1/68 C12Q1/6844 C12Q1/6876 

Abstract RU 2818356 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to molecular biology. Described is a method for assessing the resistance of squamous cell carcinoma of throat to radiation therapy. Method involves a polymerase chain reaction (PCR) method, which enables to determine the level of expression of microRNA, which is described by protocols for preparing the PCR and the obtained results. PCR involves preparing a solution using a kit comprising a test tube with a mixture of lyophilized 22 primers for 11 microRNA hsa-miR-128-3p, hsa-miR-20a-5p, hsa-miR-17-5p, hsa-let-7e-5p, hsa-miR-135b-5p, hsa-miR-125b-5p, hsa-miR-21-5p, hsa-miR-16-5p, hsa-miR-210, hsa-miR-23a-3p and hsa-miR-34c-5p.

EFFECT: more accurate and reliable assessment of resistance of squamous cell carcinoma of throat to radiation.

2 cl, 1 tbl

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RU 2 818 356 C1

Authors

Pogodina Evgeniya Sergeevna

Rastorgueva Evgeniya Vladimirovna

Yurova Elena Valerevna

Beloborodov Evgenij Alekseevich

Sugak Dmitrij Evgenevich

Saenko Yurij Vladimirovich

Fomin Aleksandr Nikolaevich

Dates

2024-05-02Published

2022-11-30Filed