AUTOIMMUNE GASTRITIS PATHOANATOMICAL DIAGNOSTICS METHOD Russian patent published in 2024 - IPC G01N33/50 A61B5/00 

FIELD: medicine; pathological anatomy; gastroenterology.

SUBSTANCE: invention can be used for postmortem diagnosis of autoimmune gastritis. Biopsy material of the gastric mucosa is examined according to the following histological criteria, which are assigned the corresponding points: state of the main glands of the gastric body and the presence of pseudopyloric and intestinal metaplasia/atrophy; presence of foveolar hyperplasia; presence of hyperplasia of neuroendocrine cells; presence of histological signs of Helicobacter pylori infection; presence of inflammatory changes in the antrum. Further, the scores are summed up to calculate an autoimmune gastritis (AIG) index. If index is 6–8 points, the patient is not diagnosed with AIG. If the AIG index is 9–10 points, a higher probability of the diagnosis of AIG is indicated. If the AIG index is more than 11 points, AIG is diagnosed.

EFFECT: invention provides a wider range of technical means in the pathological diagnosis of autoimmune gastritis by including the immunohistochemistry results into the algorithm.

1 cl, 4 tbl, 3 dwg, 3 ex