METHOD FOR GENOTYPING A POLYMORPHIC LOCUS RS11024030 (T>C) OF THE C11ORF58 GENE IN A HUMAN BY REAL-TIME PCR USING ALLELE-SPECIFIC FLUORESCENT PROBES Russian patent published in 2024 - IPC C12Q1/68 C12Q1/6844 C12Q1/6876 

Abstract RU 2819255 C1

FIELD: biotechnology.

SUBSTANCE: what is described is a method for genotyping a polymorphic locus rs11024030 (T>C) of the C11orf58 gene in a human by real-time PCR using allele-specific fluorescent probes. Identification of allelic variants of T/C rs11024030 of gene C11orf58 is carried out using the developed primers.

EFFECT: development of simple and economically feasible method of genotyping of single-nucleotide polymorphism rs11024030 (T>C), localized in position chr11:16749066 (GRCh38) of gene C11orf58 by real-time polymerase chain reaction using allele-specific signalling probes containing FAM and ROX fluorophores.

1 cl, 1 dwg, 1 ex

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RU 2 819 255 C1

Authors

Bushueva Olga Iurevna

Polonikov Aleksei Valerevich

Kobzeva Kseniia Andreevna

Dates

2024-05-16Published

2023-12-27Filed