METHOD FOR GENOTYPING POLYMORPHIC LOCUS rs3802963 (CG) OF C11orf58 GENE IN HUMANS BY REAL-TIME PCR USING ALLELE-SPECIFIC FLUORESCENT PROBES Russian patent published in 2024 - IPC C12Q1/68 C12Q1/6806 C12Q1/6876 

Abstract RU 2819936 C1

FIELD: biotechnology.

SUBSTANCE: described is a method for genotyping a polymorphic locus rs3802963 (C>G) of the C11orf58 gene by real-time PCR using allele-specific fluorescent probes, differs by the fact that identification of allelic variants of rs3802963 (C>G) of the C11orf58 gene is carried out using a forward primer rs3802963 5'-TCCTCAGCCCTCACCTCATA-3', reverse primer rs3802963 5'-TGGGCTAGGAGCTAGGACAA-3', rs3802963-C-allele-specific fluorescent-labelled probe 5'-FAM-TACTGCACTGCCG-RTQ1-3', rs3802963-G-allele-specific fluorescent-labelled probe 5'-ROX-TACTGCAGTGCCG-BHQ2-3'.

EFFECT: invention widens the range of methods for genotyping polymorphic variants of the C11orf58 gene.

1 cl, 1 dwg, 1 ex

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RU 2 819 936 C1

Authors

Bushueva Olga Iurevna

Kobzeva Kseniia Andreevna

Medvedeva Marina Viktorovna

Dates

2024-05-28Published

2023-12-23Filed