METHOD FOR GENOTYPING POLYMORPHIC LOCUS rs10832676 (A>G) OF C11orf58 GENE IN HUMANS BY REAL-TIME PCR USING ALLELE-SPECIFIC FLUORESCENT PROBES Russian patent published in 2024 - IPC C12Q1/68 C12Q1/6806 C12Q1/6876 

Abstract RU 2819930 C1

FIELD: biotechnology.

SUBSTANCE: disclosed is a method for genotyping a polymorphic locus rs10832676 (A>G) of the C11orf58 gene in humans by PCR using allele-specific fluorescent probes, according to the invention, the rs10832676 (A>G) of the C11orf58 gene allelic variants are identified using primers 5′-CACTTGAAGTTTTTCGGTAGTATCA-3′, 5′-AAACACCATGTGAAGGTGAGAA-3′ and probes 5′-FAM-CTTCACAGATGATTG-RTQ1-3′, 5′-ROX-CTTCACAGGTGATTG-BHQ2-3′.

EFFECT: invention widens the range of methods for genotyping polymorphic variants of the C11orf58 gene, is characterized by simplicity, accuracy and low cost.

1 cl, 1 dwg, 1 ex

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RU 2 819 930 C1

Authors

Bushueva Olga Iurevna

Kudriavtsev Viacheslav Grigorevich

Dates

2024-05-28Published

2023-12-26Filed