FIELD: medicine.
SUBSTANCE: invention relates to a method for preparing an adhesive composition from an initial blood composition. Method for preparing an adhesive composition from an initial blood composition, wherein said method involves the following steps: a) obtaining an initial blood composition of human or animal origin, which is platelet-rich blood plasma; b) increasing the temperature of the initial blood composition to temperature of 40–53 °C; c) centrifuging the blood composition and d) activating thrombocytes with supernatant PRP 333 mcl and 20 mcl of calcium for each 1 ml of the composition and formation of a fibrin-containing composition containing a fibrin clot, with a coagulation time of less than 4.5 minutes.
EFFECT: method described above enables to obtain an adhesive composition with desired biological or therapeutic properties, obtained from an initial blood composition rich in thrombocytes and/or growth factors, which can be prepared during surgery and can have high tissue adhesion.
9 cl, 6 dwg, 6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| COMPOSITION BASED ON BLOOD COMPOSITION ENRICHED WITH THROMBOCYTES AND/OR GROWTH FACTORS AND CONTAINS GEL-LIKE PROTEINS, AND METHOD FOR PRODUCTION THEREOF | 2014 |
|
RU2697249C2 |
| METHOD, TEST TUBE AND DEVICE FOR MAKING OF COMPOSITIONS FOR WOUND HEALING | 2011 |
|
RU2667964C1 |
| METHOD, TEST TUBE AND DEVICE FOR MAKING OF COMPOSITIONS FOR WOUND HEALING | 2011 |
|
RU2614722C2 |
| METHOD OF PRODUCING THROMBOCYTE-RICH PLASMA AND METHOD FOR PRODUCING THROMBO-FIBBRIN GEL OR CLOT WITH SERUM, CONTAINING GROWTH FACTORS FROM UNSTABILISED VENOUS BLOOD | 2019 |
|
RU2717448C1 |
| METHOD OF OBTAINING A PLATELET-RICH FIBRIN MATRIX WITH AN OSTEOREPLACEMENT MATERIAL FIXED IN THE FIBRIN NETWORK OR AN AUTOCRUMB FROM BONE OR CARTILAGE TISSUE | 2023 |
|
RU2802583C1 |
| METHOD OF PRODUCING PLATELET-ENRICHED FIBRIN MATRIX OF VARIOUS SHAPES AND SIZES | 2023 |
|
RU2811233C1 |
| METHOD OF TREATING CORNEAL DEFECTS OF VARIOUS ETIOLOGIES | 2023 |
|
RU2809012C1 |
| NANODISPERSED PLASTIC BIOENGINEERING COMPOSITION BASED ON CERIUM DIOXIDE FOR REPLENISHING THE VOLUME OF BONE TISSUE | 2021 |
|
RU2793324C1 |
| METHOD OF PREPARATION OF AUTOLOGOUS TWO-COMPONENT FIBRIN ADHESIVE | 2019 |
|
RU2704256C1 |
| SERUM FRACTION OF THROMBOCYTE-ENRICHED FIBRIN | 2014 |
|
RU2711330C2 |
