METHOD FOR PREDICTING THE RISK OF DEVELOPING TYPE 2 DIABETES IN RESIDENTS OF CENTRAL RUSSIA BASED ON GENOTYPING OF THE rs11073891 POLYMORPHISM OF THE ANPEP GENE Russian patent published in 2023 - IPC G01N33/50 C12Q1/6806 C12Q1/6827 C12Q1/686 C12Q1/6876 C12Q1/6883 

Abstract RU 2803636 C1

FIELD: medicine, medical diagnostics.

SUBSTANCE: invention can be used to predict the risk of developing type 2 diabetes in residents of Central Russia. A sample of peripheral venous blood is taken and DNA is extracted. Analysis of the polymorphic variant of the aminopeptidase gene ANPEP rs11073891 (A>C) is carried out. If the rs11073891-A/A genotype is detected, an increased risk of developing type 2 diabetes is predicted. When rs11073891-A/C or rs11073891-C/C genotypes are detected, a low risk of developing type 2 diabetes is predicted.

EFFECT: method provides for obtaining new criteria for assessing the risk of developing type 2 diabetes in residents of Central Russia according to the genetic polymorphism rs11073891 (A>C).

1 cl, 1 dwg, 1 tbl, 3 ex

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RU 2 803 636 C1

Authors

Azarova Iuliia Eduardovna

Klesova Elena Iurevna

Polonikov Aleksei Valerevich

Korviakova Iaroslava Evgenevna

Dates

2023-09-18Published

2023-03-06Filed