FIELD: biotechnology.
SUBSTANCE: disclosed is a recombinant bacterium Corynebacterium glutamicum for producing hyaluronic acid, comprising switched off or knocked out exopolysaccharide genes cg0420 and/or cg0424, wherein said bacterium contains a gene coding hyaluronate synthase, and a gene coding hemoglobin VHb. Also disclosed is a method of constructing said recombinant bacteria, a method of producing hyaluronic acid using said recombinant bacteria.
EFFECT: invention provides production of hyaluronic acid with increased output and purity.
8 cl, 5 dwg, 3 ex
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