FIELD: biotechnology.
SUBSTANCE: disclosed is a Saccharomyces cerevisiae yeast strain for testing environmental mutagens, having the genotype MATα ade2-248 Ieu2-3,112 ura3-160.188 apn1Δ hmo1Δ. Strain is susceptible to environmental genotoxicants damaging DNA nitrogenous bases, as well as the inability of mutations of apn1Δ and hmo1Δ reverting to wild type.
EFFECT: invention provides testing of mutagens causing damage to DNA nitrogenous bases.
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Authors
Dates
2024-08-29—Published
2023-11-29—Filed