BIOREACTOR SYSTEM AND APPLICATION THEREOF Russian patent published in 2024 - IPC C12M3/02 C12M1/00 

Abstract RU 2825841 C1

FIELD: biotechnology.

SUBSTANCE: group of inventions relates to a bioreactor system for culturing cells without cell walls and to a method for culturing cells using a bioreactor system. Bioreactor system includes: a container; oscillator; ventilation means designed to supply oxygen-containing gas into the container from the upper part of the container, and a culture medium poured into the container. Container comprises a hollow cylinder with diameter D1 and height H1, as well as a hollow round cone with upper diameter D2, lower diameter D3 and height H2, wherein the hollow cylinder is connected to the upper surface of the hollow round cone, D1 = D2. Oscillator contains a movable platform and a motor driving the platform. Container is fixed on the above oscillator platform so that to provide the possibility of eccentric movement of the container with a certain eccentricity and rotation speed.

EFFECT: declared group of inventions provides stable cell growth and proliferation, as well as high cell survival.

10 cl, 6 dwg, 15 tbl, 4 ex

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RU 2 825 841 C1

Authors

Lo, Shun

Khu, Fulin

Yuan, Shipin

Khou, Tszyue

Sun, Tszinpej

Dates

2024-09-02Published

2020-09-04Filed