KERATIN BD-13, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Russian patent published in 2024 - IPC C07K14/47 C12P21/02 A61K38/17 A61P11/00 A61P25/08 A61P29/00 

Abstract RU 2825991 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to keratin variants. Invention provides therapeutic use of keratin, having efficacy in reducing body temperature rise in fever model in SD rats and prolonging the latency of seizures in class III epilepsy in mice, expectorant action in the method with releasing phenol red in mice, antitussive action in a method for stimulating cough using an aqueous solution of ammonia in mice and a tendency to reduce the number of writhing in mice and the potential for analgesic action in acetic acid-induced writhing in ICR mice.

EFFECT: invention can be used in medicine to produce a drug having antipyretic, analgesic, antitussive, expectorant, anticonvulsant and antiepileptic action.

10 cl, 3 dwg, 9 tbl, 14 ex

Similar patents RU2825991C1

Title Year Author Number
KERATIN BD-6, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 2020
  • Yuj, Shishan
  • Van, Syaolyan
  • Shi, Gozhu
  • Lyu, Yunbao
  • Li, Yun
  • Van, Lin
  • Li, Tszyan
  • Fen, Nan
  • Li, Mi
RU2825993C1
KERATIN BD-11, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 2020
  • Yuj, Shishan
  • Van, Syaolyan
  • Fu, Tszyan
  • Li, Yun
  • Chzhan, Mi
  • Fen, Nan
  • Su, Gochzhu
  • Li, Tszyan
  • Lyu, Yunbao
RU2825992C1
KERATIN BD-3, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 2020
  • Yuj, Shishan
  • Van, Syaolyan
  • Tsyuj, Tszin
  • Fu, Tszyan
  • Van, Lin
  • Tsaj, Tsze
  • Li, Mi
  • Fen, Nan
  • Shi, Gozhu
RU2815384C1
KERATIN BD-10, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 2020
  • Yuj, Shishan
  • Van, Syaolyan
  • Fu, Tszyan
  • Lyu, Yunbao
  • Fen, Nan
  • Chzhan, Mi
  • Shi, Gozhu
  • Tsaj, Tsze
RU2823655C1
KERATIN BD-1, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 2020
  • Yuj, Shishan
  • Van, Syaolyan
  • Tsyuj, Tszin
  • Shi, Gozhu
  • Fu, Tszyan
  • Van, Lin
  • Fen, Nan
  • Syuj, Shaofen
RU2825994C1
KERATIN BD-4, PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF 2020
  • Yu Shishan
  • Wang Xiaoliang
  • Qu Jing
  • Li Mi
  • Su Guozhu
  • Wang Ling
  • Cai Jie
  • Xu Shaofeng
  • Fu Jiang
RU2824893C1
ANTI-αvβ8 ANTIBODIES AND COMPOSITIONS AND THEIR USE 2019
  • Nissen, Kajl, Stiven
  • Semyuel, Dkharmaradzh
  • Kholst, Charlz, Rej
  • Driver, Mettyu, Ross
  • Sheppard, Din
  • Ekkherst, Rozmeri, Dzh.
  • Atakilit, Amkha
  • Mejer, Dominik
  • Rondon, Isaak, Dzh.
  • Dal Porto, Dzhozef
RU2812478C2
ANTIBODIES AGAINST TIGIT AND APPLICATION THEREOF 2019
  • Lee, Kwang-Hoon
  • Lee, June Hyung
  • Lee, Na Rae
  • Jeong, Eunjeong
  • Park, Young Bong
  • Chang, Nakho
  • Lee, Eun-Jung
  • Kim, Ki Hong
  • Choi, Sunghyun
  • Choi, Byung Hyun
  • Park, Ju Young
  • Song, Moo Young
  • Lee, Jong-Seo
  • Kim, Kyu-Tae
  • Ko, Bong-Kook
RU2750705C1
ANTI-PD-1 ANTIBODY AND USE THEREOF 2017
  • Li Qiang
  • Zheng Yuncheng
  • Yang Lu
  • Ma Xinlu
  • Li Yuanli
RU2739610C1
ANTI-MESOTHELIN ANTIBODY AND CONJUGATE THEREOF WITH MEDICINAL PRODUCTS 2019
  • Fang, Jianmin
  • Huang, Changjiang
  • Jiang, Jing
  • Ye, Hui
  • Li, Shenjun
  • Xu, Qiaoyu
  • Luo, Wenting
  • Wang, Mingxue
RU2747995C1

RU 2 825 991 C1

Authors

Yuj, Shishan

Van, Syaolyan

Lyu, Yunbao

Tsyuj, Tszin

Li, Tszyan

Fen, Nan

Li, Yun

Chzhan, Mi

Su, Gochzhu

Dates

2024-09-02Published

2020-10-28Filed