KERATIN BD-11, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Russian patent published in 2024 - IPC C07K14/47 C12P21/02 A61K38/17 A61P11/00 A61P25/08 A61P29/00 

Abstract RU 2825992 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to keratin variants. Invention provides therapeutic use of keratin, having efficacy in reducing body temperature rise in fever model in SD rats and prolongation of seizure latency in class III epilepsy in mice; expectorant action in method with release of phenol red in mice; antitussive action in a method for stimulating coughing with an aqueous solution of ammonia in mice and a tendency to reduce the number of writhing in mice and potential analgesic action in acetic acid-induced writhing in ICR mice.

EFFECT: invention can be used in medicine to produce a drug having antipyretic, analgesic, antitussive, expectorant, anticonvulsant and antiepileptic action.

10 cl, 3 dwg, 9 tbl, 14 ex

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RU 2 825 992 C1

Authors

Yuj, Shishan

Van, Syaolyan

Fu, Tszyan

Li, Yun

Chzhan, Mi

Fen, Nan

Su, Gochzhu

Li, Tszyan

Lyu, Yunbao

Dates

2024-09-02Published

2020-10-28Filed