KERATIN BD-1, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Russian patent published in 2024 - IPC C07K14/47 C12P21/02 A61K38/17 A61P11/00 A61P25/08 A61P29/00 

Abstract RU 2825994 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to versions of keratin and can be used in medicine when producing a drug having antipyretic, analgesic, antitussive, expectorant, anticonvulsant and antiepileptic action.

EFFECT: invention provides the therapeutic use of keratin, having efficacy in reducing a rise in body temperature in a fever model in SD rats and prolonging the latency of seizures in class III epilepsy in mice; expectorant action in method with release of phenol red in mice; antitussive action in a method for stimulating coughing with an aqueous solution of ammonia in mice and a tendency to reduce the number of writhing in mice and potential analgesic action in acetic acid-induced writhing in ICR mice.

10 cl, 3 dwg, 9 tbl, 14 ex

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RU 2 825 994 C1

Authors

Yuj, Shishan

Van, Syaolyan

Tsyuj, Tszin

Shi, Gozhu

Fu, Tszyan

Van, Lin

Fen, Nan

Syuj, Shaofen

Dates

2024-09-02Published

2020-10-28Filed