KERATIN BD-6, METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Russian patent published in 2024 - IPC C07K14/47 C12P21/02 A61K38/17 A61P11/00 A61P25/08 A61P29/00 

Abstract RU 2825993 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to versions of keratin and can be used in medicine when producing a drug having antipyretic, analgesic, antitussive, expectorant, anticonvulsant and antiepileptic action.

EFFECT: invention provides the therapeutic use of keratin, having efficacy in reducing a rise in body temperature in a fever model in SD rats and prolonging the latency of seizures in class II, class III and class IV epilepsy in mice; expectorant action in method with release of phenol red in mice; antitussive action in the method of stimulating cough with the help of aqueous ammonia solution in mice, a tendency to reduce the number of writhings in mice and potential analgesic action in acetic acid-induced writhings in ICR mice.

10 cl, 3 dwg, 9 tbl, 14 ex

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RU 2 825 993 C1

Authors

Yuj, Shishan

Van, Syaolyan

Shi, Gozhu

Lyu, Yunbao

Li, Yun

Van, Lin

Li, Tszyan

Fen, Nan

Li, Mi

Dates

2024-09-02Published

2020-10-28Filed