METHOD FOR PREDICTION OF DEVELOPMENT OF CARIES BY RESULTS OF ANALYSIS OF PRODUCTS OF ACID METABOLISM OF MICROFLORA OF DENTAL DEPOSIT Russian patent published in 2024 - IPC G01N33/487 A61B5/00 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to dentistry, can be used in assessing the probability and intensity of processes leading to caries development. To analyse the biomaterial, a dental deposit is sampled on a sterile swab from at least one tooth. Analysis of the biomaterial is carried out using a device – a portable electronic nose "MAG-8" with replaceable gas piezosensors of OAB-type with three different sorbents. Piezoelectric sensor sorbents used are separate phases of 2–4 mcg of carboxylated carbon nanotubes for calculating S1, zirconyl nitrate for calculating S2 and hydroxyapatite for calculating S3. For the piezoelectric sensors to reach the operating mode, the device is heated for 20 minutes. Then the swab is placed in a detection cell with sensors not later than 3 minutes from the moment of sampling, and the beginning of measurements is started by activating the software of the device, which is combined with the computer. Signal of each individual piezosensor is recorded with a step of one second. Areas under the output curves of each sensor S1, S2, S3 are recorded in the software, and the areas under the output curves of each sensor S1, S2, S3 are measured respectively. Quotient of the output areas is determined using the formula k=S1/S2/S3. If the value of k is less than or equal to 0.30, then the sample is determined as selected with an error and the analysis is recommended to be repeated; if k is more than 0.30 and less than 1.5, then the sample is defined as the absence of carious processes; if k is greater than or equal to 1.5 and less than 2.5, the test is defined as a high probability of developing caries; if k is greater than or equal to 2.5, the sample is determined as the presence of a carious process.

EFFECT: method, due to rapid testing of dental plaque for predicting the development of caries, enables to start preventive and therapeutic procedures in a timely manner, reduce the intensity of tooth decay, as well as injuries and discomfort of the patient during the examination, reduce the total examination time and the volume of the load on the doctor without loss of information quality.

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