PHARMACEUTICAL COMPOSITION OF PYRAZOLE Russian patent published in 2024 - IPC A61K9/16 A61K9/20 A61K31/4155 A61K47/14 A61K47/22 A61K47/34 A61P17/00 A61P17/04 

Abstract RU 2829944 C1

FIELD: chemistry; pharmaceutics.

SUBSTANCE: group of inventions relates to a solid pharmaceutical composition for treating atopic dermatitis, to versions of a method for preparing it, as well as to versions of a method of treating atopic dermatitis, which involve administering to an animal in need thereof an effective amount of said solid pharmaceutical composition. Disclosed composition is a tablet and contains: a) a pharmaceutically effective amount of a compound of formula (I) and b) a pharmaceutically acceptable carrier which includes a filler, a disintegrant, a lubricant and a surfactant which is d-α-tocopheryl polyethylene glycol 1,000 succinate (TPGS), wherein the amount of TPGS in composition is 1.0–10.0 wt./wt.%.

EFFECT: group of inventions provides higher bioavailability of the compound of formula (I).

26 cl, 3 dwg, 10 tbl, 7 ex

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RU 2 829 944 C1

Authors

Brown, Chad, D

Kulczar, Christopher, D

Wang, Chen-Chao

Fung, Michelle, H

Dates

2024-11-11Published

2020-12-18Filed