FIELD: chemistry; pharmaceutics.
SUBSTANCE: group of inventions relates to a solid pharmaceutical composition for treating atopic dermatitis, to versions of a method for preparing it, as well as to versions of a method of treating atopic dermatitis, which involve administering to an animal in need thereof an effective amount of said solid pharmaceutical composition. Disclosed composition is a tablet and contains: a) a pharmaceutically effective amount of a compound of formula (I) and b) a pharmaceutically acceptable carrier which includes a filler, a disintegrant, a lubricant and a surfactant which is d-α-tocopheryl polyethylene glycol 1,000 succinate (TPGS), wherein the amount of TPGS in composition is 1.0–10.0 wt./wt.%.
EFFECT: group of inventions provides higher bioavailability of the compound of formula (I).
26 cl, 3 dwg, 10 tbl, 7 ex
Title | Year | Author | Number |
---|---|---|---|
PHARMACEUTICAL COMPOSITION OF PYRAZOLE COMPOUND DISPERSED IN POLYMER MATRIX | 2020 |
|
RU2826604C1 |
PHARMACEUTICAL COMPOSITION AND ITS ADMINISTERING | 2013 |
|
RU2802442C2 |
PHARMACEUTICAL COMPOSITION AND INTRODUCTION THEREOF | 2013 |
|
RU2692779C2 |
PHARMACEUTICAL COMPOSITIONS OF MONTELUCAST AND LEVOCETIRISINE | 2013 |
|
RU2677649C2 |
PHARMACEUTICAL COMPOSITION INCLUDING IMIDAZOLINE DERIVATIVE | 2017 |
|
RU2749135C2 |
PHARMACEUTICAL COMPOSITION INCLUDING SODIUM ALKYL SULPHATE | 2019 |
|
RU2759746C1 |
SOLID DISPERSIONS AND PHARMACEUTICAL COMPOSITIONS INCLUDING SUBSTITUTED INDANE, AND METHODS FOR PRODUCTION AND APPLICATION THEREOF | 2019 |
|
RU2772693C1 |
PHARMACEUTICAL COMPOSITIONS CONTAINING DGAT1 INHIBITOR | 2011 |
|
RU2595866C2 |
DOSAGE FORMS WITH A PLEASANT TASTE | 2020 |
|
RU2789487C1 |
SOLID PHARMACEUTICAL PREPARATION, METHOD OF ITS PREPARATION AND USE | 2021 |
|
RU2809722C1 |
Authors
Dates
2024-11-11—Published
2020-12-18—Filed