METHOD FOR PREDICTION OF RISK OF ADVERSE CARDIOVASCULAR EVENTS WITHIN 12 MONTHS AFTER CORONARY BYPASS SURGERY Russian patent published in 2024 - IPC G01N33/68 G01N33/49 

Abstract RU 2830502 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to cardiology, and can be used to predict the risk of adverse cardiovascular events within 12 months after coronary bypass surgery. Blood serum of the patients with ischemic heart disease scheduled for coronary artery bypass surgery is examined for the concentration of growth/differentiation factor 15 (GDF-15), pg/ml, and the ratio of neutrophils to blood lymphocytes (NEUT/LYMPH). Risk of adverse cardiovascular events is calculated by formula: p = GDF-15 × (NEUT/LYMPH), where p is the probability of adverse cardiovascular events within 12 months after coronary bypass surgery. If the p value is 3,216 and more, a high risk of unfavourable cardiovascular events is predicted.

EFFECT: method enables predicting the risk of adverse cardiovascular events for 12 months after coronary artery bypass grafting by measuring blood serum of patients with coronary artery disease planned for coronary artery bypass grafting, concentration of GDF-15 and ratio of neutrophils to blood lymphocytes.

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RU 2 830 502 C1

Authors

Garganeeva Alla Anatolevna

Kuzheleva Elena Andreevna

Tukish Olga Viktorovna

Kondratev Mikhail Iurevich

Dates

2024-11-20Published

2024-04-04Filed