FIELD: pharmaceutics.
SUBSTANCE: group of inventions relates to a haemostatic dressing and a method for production thereof. Haemostatic dressing contains a haemostatic composition containing a haemostatic agent, a bioadhesive agent and an antifibrinolytic agent; where said bioadhesive agent contains one or more substances selected from: a cross-linked polymer of acrylic acid, wherein said polymer has a molecular weight of at least about 50,000 g/mol; or a carbomer, or a high molecular weight polymer of acrylic acid cross-linked with divinyl glycol, or salts of polyacrylic acid cross-linked with divinyl glycol, wherein said haemostatic agent is chitosan or a chitosan salt, and said antifibrinolytic agent is tranexamic acid, and said haemostatic agent is contained in an amount of at least 20 wt.% from the weight of said composition, said bioadhesive agent is contained in amount of 5 to 10 wt.% of the weight of said composition, and said antifibrinolytic agent is contained in amount of 10 to 50 wt.% from the weight of said composition. Method for producing the haemostatic dressing involves the stages of combining the haemostatic agent with a bioadhesive agent and an antifibrinolytic agent.
EFFECT: above described group of inventions is effective in arresting blood flow in both standard and coagulopathic wound injuries, while achieving reduced compression time.
11 cl, 1 ex
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Authors
Dates
2024-11-22—Published
2019-02-14—Filed