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(19)

(11)

2 831 156

(13)

(51)

IPC

C07D471/04(2006-01-01)

C07D487/04(2006-01-01)

C07D487/08(2006-01-01)

C07D487/10(2006-01-01)

A61K31/437(2006-01-01)

A61K31/4427(2006-01-01)

A61K31/496(2006-01-01)

A61K31/497(2006-01-01)

A61K31/501(2006-01-01)

A61K31/506(2006-01-01)

A61K31/551(2006-01-01)

A61P9/00(2006-01-01)

A61P9/04(2006-01-01)

A61P9/10(2006-01-01)

A61P9/12(2006-01-01)

A61P1/16(2006-01-01)

A61P3/12(2006-01-01)

A61P13/12(2006-01-01)

(21) (22)

Application

2023120694, 2023-08-07

(24)

Start date

2023-08-07

(22)

Actual filing date

2023-08-07

(45)

Published

2024-12-02

(72)

Inventor

George PascalStrushkevich Natalya VladimirovnaDzhordzh Paskal

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennostyu Medikals" Medikals")

HUMAN ALDOSTERONE SYNTHASE (CYP11B2) INHIBITORS Russian patent published in 2024 - IPC C07D471/04 C07D487/04 C07D487/08 C07D487/10 A61K31/437 A61K31/4427 A61K31/496 A61K31/497 A61K31/501 A61K31/506 A61K31/551 A61P9/00 A61P9/04 A61P9/10 A61P9/12 A61P1/16 A61P3/12 A61P13/12

Abstract RU 2831156 C1

FIELD: organic chemistry; pharmacology; medicine.

SUBSTANCE: group of inventions includes individual compounds specified in the claim, a pharmaceutical composition containing them, and use thereof.

EFFECT: compounds given in the claim for inhibiting human cytochrome P450 11B2 (CYP11B2) activity and reducing the level of the hormone aldosterone.

8 cl, 3 tbl, 28 ex

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RU 2 831 156 C1

Authors

George Pascal

Strushkevich Natalya Vladimirovna

Dzhordzh Paskal

Dates

2024-12-02—Published

2023-08-07—Filed