BIOCOMPATIBLE INJECTED BONE CEMENT BASED ON CALCIUM-MAGNESIUM PHOSPHATE PHASES WITH ADDITION OF CARBOXYMETHYL CELLULOSE FOR FILLING BONE DEFECTS Russian patent published in 2024 - IPC A61L24/02 A61L24/08 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to biocompatible injected bone cement. Biocompatible injected bone cement based on calcium-magnesium phosphate phases with addition of carboxymethyl cellulose for filling bone defects is characterized by that the cement powder contains phases: stanfieldite Mg₃Ca₃(PO₄)₄ in amount of 0-90 wt.%, whitlockite Ca₉Mg(HPO₄)(PO₄)₆ in amount of up to 10 wt.% and magnesium oxide MgO in amount of 5-15 wt.%, and the fact that the cement liquid based on aqueous 3.5 M solution of Na₂HPO₄ and/or NaH₂PO₄ salts contains an additive polymer of carboxymethyl cellulose in concentration of 0.2-2.0 wt.%, characterized by pH level of 3.3-3.8, ratio of initial components when mixing CP:CL is 1.5-2.

EFFECT: above described bone cement has setting time of 11-18 minutes, neutral pH of 6.8-7.3, strength of at least 10 MPa, contains the main cement phases – stanfieldite (Mg₃Ca₃(PO₄)₄) and newberiit MgHPO₄(H₂O)₃, and also has injectability of at least 60%.

1 cl, 6 dwg, 1 tbl, 6 ex