FIELD: medicine.
SUBSTANCE: method involves preparing mineral phases forming the basis of an inorganic matrix of human bone tissue in an artificial medium close to such in the individuals suffering coxarthrosis. That involves preparing the above simulative medium at pH 7.80+0.05. The medium has thee following composition: CaCl2 - 1.1766 g/l, Na2HPO412H2O - 6.5514 g/l, NaCl - 3.1892 g/l, MgCl2-6H2O - 0.4764 g/l, NaHCO3 - 2.2680 g/l, Na2SO4 - 1.6188 g/l, KCl - 0.3427 g/l. After 30 minutes, the medium is examined for hydroxylapatite compositionally similar to apatite of the bone intercellular substance in the patients suffering coxarthrosis.
EFFECT: simulating bone mineralisation in coxarthrosis in vitro and detection of the environment promoting mineral phase deposition in the human joint synovial fluid, enables developing the more effective methods to prevent the development of the given disease.
3 tbl, 4 dwg
