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2 834 294

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IPC

C07C211/27(2006-01-01)

A61K31/137(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2023131688, 2023-12-04

(24)

Start date

2023-12-04

(22)

Actual filing date

2023-12-04

(45)

Published

2025-02-05

(72)

Inventor

Mokrov Grigorij VladimirovichKryzhanovskij Sergej AleksandrovichVorobeva Tatyana YurevnaBiryukova Valentina EvgenevnaBarchukova Elena IgorevnaVititnova Marina BorisovnaTsorin Iosif BorisovichKolik Larisa GennadevnaDurnev Andrej DmitrievichGudasheva Tatyana AleksandrovnaDorofeev Vladimir Lvovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Issledovatelskij Tsentr Originalnykh I Perspektivnykh Biomeditsinskikh I Farmatsevticheskikh Tekhnologij"

N-BENZYL-N-(2-((2,3,4-TRIMETHOXYBENZYL)AMINO)ETHANE-1,2-DIAMINES, HAVING CARDIOTROPIC ACTIVITY Russian patent published in 2025 - IPC C07C211/27 A61K31/137 A61P9/10

Abstract RU 2834294 C1

FIELD: chemistry; medicine.

SUBSTANCE: invention refers to chemistry and medicine, namely to N¹-benzyl-N²-(2-((2,3,4-trimethoxybenzyl)amino)ethyl)ethane-1,2-diamines of formula I and their trihydrochlorides. In formula I, R¹-R³ can be hydrogen atoms, methoxy- or hydroxy-groups, provided that only one of substitutes R¹-R³ can be methoxy-group.

EFFECT: compounds of formula I exhibit cardiotropic (anti-ischemic and antiarrhythmic) activity.

7 cl, 5 tbl, 12 ex

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RU 2 834 294 C1

Authors

Mokrov Grigorij Vladimirovich

Kryzhanovskij Sergej Aleksandrovich

Vorobeva Tatyana Yurevna

Biryukova Valentina Evgenevna

Barchukova Elena Igorevna

Vititnova Marina Borisovna

Tsorin Iosif Borisovich

Kolik Larisa Gennadevna

Durnev Andrej Dmitrievich

Gudasheva Tatyana Aleksandrovna

Dorofeev Vladimir Lvovich

Dates

2025-02-05—Published

2023-12-04—Filed