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2 791 576

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IPC

C07C217/58(2006-01-01)

A61K31/135(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2021102977, 2021-02-09

(24)

Start date

2021-02-09

(22)

Actual filing date

2021-02-09

(45)

Published

2023-03-10

(72)

Inventor

Seredenin Sergej BorisovichBarchukov Vladimir ValerevichBarchukova Elena IgorevnaMokrov Grigorij VladimirovichKryzhanovskij Sergej AleksandrovichStolyaruk Valerij NikolaevichVititnova Marina BorisovnaTsorin Iosif BorisovichGudasheva Tatyana AleksandrovnaDurnev Andrej Dmitrievich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Institut Farmakologii Imeni V.V. Zakusova"

BIS(ALKOXYBENZYL)ALKANDIAMINES WITH CARDIOTROPICACTIVITY Russian patent published in 2023 - IPC C07C217/58 A61K31/135 A61P9/10

Abstract RU 2791576 C2

FIELD: organic chemistry.

SUBSTANCE: in particular, the invention includes new bis(alkoxybenzyl)alkanediamines of general formula I and their physiologically acceptable salts, preferably dihydrochlorides of general formula II (I* 2HCl), except for 1,3-bis((2,3,4-trimethoxybenzyl)amino)propane, which has cardiotropic activity. In this formula, n may be from 1 to 6, R¹ and R² may be hydrogen atoms, hydroxyl and alkyl groups. FIELD: invention relates to a method for treating ischemic disease and arrhythmias by administering effective amounts of compounds of general formula I.

4 cl, 4 tbl, 9 ex

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RU 2 791 576 C2

Authors

Seredenin Sergej Borisovich

Barchukov Vladimir Valerevich

Barchukova Elena Igorevna

Mokrov Grigorij Vladimirovich

Kryzhanovskij Sergej Aleksandrovich

Stolyaruk Valerij Nikolaevich

Vititnova Marina Borisovna

Tsorin Iosif Borisovich

Gudasheva Tatyana Aleksandrovna

Durnev Andrej Dmitrievich

Dates

2023-03-10—Published

2021-02-09—Filed