FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to obtaining modified peptide epitopes, and can be used in medicine for treating obesity. Disclosed is a peptide which can be recognized by a CD4+ T-cell for inducing a humoral immune response, wherein the peptide consists of RNVPPIFNDVYWIAFZaK(Cha)VAAWTLKAACR, where a denotes the D-form of alanine, (Cha) denotes L-cyclohexylalanine and Z denotes 6-aminohexanoic acid. Also disclosed is a composition for treating obesity containing said peptide.
EFFECT: invention enables to obtain a peptide effective in reducing body weight and fat deposits.
3 cl, 25 dwg, 15 tbl, 10 ex
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Authors
Dates
2025-03-11—Published
2021-07-21—Filed