FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, particularly to a composition of an agricultural product for converting 3-keto-DON substrate into 3-epi-DON. Said agricultural product composition contains one or more polypeptides containing or consisting of the sequence SEQ ID NO. 1-14 or containing or consisting of sequence, which is at least 75% identical to any of SEQ ID NO. 1-14, and a carrier. Invention also relates to a polypeptide comprising the sequence SEQ ID NO. 1 or identical to it by at least 92%, feed and food additives and products, method of converting trichothecene containing 3-oxo group to trichothecene, a method for reducing the content of DON, a host cell and applications, including for preventing or treating mycotoxicosis.
EFFECT: present invention provides conversion of 3-keto-DON substrate into 3-epi-DON and DON products with 3-epi-DON:DON ratio of at least 25:1.
18 cl, 5 dwg, 4 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIBODIES CONTAINING POLYPEPTIDE INTEGRATED INTO FRAME REGION 3 | 2019 |
|
RU2796254C2 |
| POLYPEPTIDES THAT ARE SOLUBLE RECEPTORS OF FIBROBLAST GROWTH FACTOR 3 (sFGFR3), AND WAYS OF THEIR APPLICATION | 2017 |
|
RU2751483C2 |
| NGF ANTAGONISTS FOR MEDICAL USE | 2020 |
|
RU2829812C2 |
| VERSIONS OF Fc-REGION WITH ALTERED BINDING TO NEONATAL Fc-RECEPTOR (FcRn) FOR USE IN VETERINARY SCIENCE | 2019 |
|
RU2830231C2 |
| TREATMENT OF ABNORMAL VISCERAL FAT DEPOSITION WITH FIBROBLAST GROWTH FACTOR 3 (sFGFR3) SOLUBLE POLYPEPTIDES | 2018 |
|
RU2794170C2 |
| EMBODIMENTS OF IGG-Fc FOR USE IN VETERINARY SCIENCE | 2018 |
|
RU2814952C2 |
| COMPOSITIONS FOR PRODUCING GLUCOSE SYRUPS | 2015 |
|
RU2706297C2 |
| IL4/IL13 RECEPTOR MOLECULE FOR VETERINARY USE | 2018 |
|
RU2795591C2 |
| FUSED PROTEIN CONSTRUCTS FOR COMPLEMENT-RELATED DISEASE | 2019 |
|
RU2824402C2 |
| POLYVALENT AND POLYSPECIFIC GITR-BINDING FUSED PROTEINS | 2016 |
|
RU2753439C2 |
