FIELD: chemistry.
SUBSTANCE: invention relates to an agarofuran compound having structural formula (I):
where there is one double bond in position 2-3 of cycle A; R1 is trifluoromethyl; R2 is a C3-C4 linear alkylene; m denotes the number of groups R3 bonded to a carbon atom located in position 4 of cycle A, m=1 or 2, and if m=1, then R3 is selected from a hydrogen atom or hydroxyl; if m=2, then R3 is a deuterium atom; and R4 is selected from a hydrogen atom, a deuterium atom or a hydroxyl atom; or having structural formula (I-k):
where R1 and R2 are as defined above, use for preparing a drug for preventing and/or treating anxiety disorder and a method for preparing the compound.
EFFECT: obtaining novel agarofuran derivatives having higher activity, improved therapeutic effect and improved metabolic parameters of a drug which is used to treat mental diseases, such as anxiety disorders.
13 cl, 5 dwg, 8 tbl, 8 ex
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