METHOD OF PRODUCING COSMETIC HYDROGEL WITH THERAPEUTIC AND PROPHYLACTIC ACTION FOR TARGETED CORRECTION OF SKIN MICROBIOME AND CONTROLLED RELEASE OF ACTIVE INGREDIENT Russian patent published in 2025 - IPC A61K8/73 A61K8/9728 A61K8/34 A61Q19/00 

FIELD: cosmetic industry.

SUBSTANCE: method of producing a cosmetic hydrogel with therapeutic and preventive action for targeted correction of the skin microbiome and controlled release of an active component involves creating a polymer composition based on natural polysaccharides, homogenising the hydrogel mass, reducing temperature to 40 °C, introduction of lysates of probiotic culture and cooling to room temperature, while creation and homogenisation of hydrogel mass is carried out on the basis of sterile water with reduced content of deuterium from 10 to 100 ppm (parts per million) at 55 °C for 20 minutes and ratio of components, wt.%: sodium alginate – 0.1÷0.75%; xanthan gum – 0.1÷0.5%; cellulose gum – 0.1÷0.5%; glycerine – 1÷5%, or propylene glycol – 1÷5%, or butylene glycol – 1÷5%; as an active component, lysates of a probiotic culture of the yeast Pichia Guilliermondii VKPM Y-4316 and/or VKPM Y-4304 in amount of 5÷10%.

EFFECT: invention enables targeted correction of the skin microbiome and increased transdermal permeability of biologically active substances for external use.

1 cl, 8 dwg, 4 ex