FIELD: biotechnology; medicine.
SUBSTANCE: invention relates to field of biotechnology and medicine. Disclosed is a pharmaceutical composition having human chorionic gonadotropin (hCG) activity. Composition comprises recombinant hCG, comprising α2,3-linked sialic acid and α2,6-linked sialic acid, and includes mono (1S), di (2S), tri (3S) and tetra (4S) sialylated structures, and a pharmaceutically acceptable carrier.
EFFECT: composition has high activity, which is equal to 27477 IU hCG/mg, and recombinant hCG has a sialic acid content of 15 mol/mol protein to 25 mol/mol protein.
13 cl, 6 dwg, 11 ex
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