FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to oncology and clinical laboratory diagnostics, and can be used for prediction of risk of tumour progression in patients with breast cancer. Patient’s blood is analysed by multicolour flow cytometry for the number of endotheliocyte precursor cells (EPC), mesenchymal stem cells (MSC), haematopoietic stem cells (HSC) and populations EpCam+CD45-CD44-CD24-Ncadherin+, EpCam+CD45-CD44+CD24-Ncadherin+, EpCam-CD45-CD44+CD24-Ncadherin+, atypical/hybrid EpCam+CD45+ cells. Number of said cells is evaluated in points. If the total score is more than or equal to 7, a high risk of tumour progression is determined. If the total score is less than 7, a low risk of tumour progression is determined.
EFFECT: method provides more accurate prediction of the clinical course of the disease by determining EPC, MSC, HSC and circulating tumour cell populations in the blood of a patient with breast cancer.
1 cl, 7 dwg, 1 tbl, 2 ex
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