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1 367 487

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IPC

(21) (22)

Application

4017807/13, 1986-01-29

(22)

Actual filing date

1986-01-29

(45)

Published

1995-10-27

(72)

Inventor

Aksenova T.A.Ehl'Bert L.B.Selimov M.A.Krasil'Nikov I.V.Krotova L.I.Gribencha L.F.

RABIES VACCINE PRODUCTION METHOD Russian patent published in 1995 - IPC

Abstract SU 1367487 A1

FIELD: microbiological industry. SUBSTANCE: method involves cell culturing of Vnukovo-32 rabies virus strain. The virus-containing liquid is collected and inactivated by sequential exposure to UV- radiation and formaldehyde solution. The inactivated virus is concentrated and purified by means of ultrafiltration with the use of porous membranes and gel-filtration on porous silicon dioxide modified with polyvinyl pyrrolidon. EFFECT: higher product purity; higher reliability of inactivation. 2 cl, 2 tbl

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SU 1 367 487 A1

Authors

Aksenova T.A.

Ehl'Bert L.B.

Selimov M.A.

Krasil'Nikov I.V.

Krotova L.I.

Gribencha L.F.

Dates

1995-10-27—Published

1986-01-29—Filed