FIELD: biotechnology. SUBSTANCE: recombinant DNA has two adjoining copies of gene of HBs-antigen of hepatitis virus B to which of each protein promoter 7.5 kD of vaccine virus is preceded. Both copies were flanked by the sequences Hind III-J-fragment of vaccine virus DNA. Recombinant strain produces up to 2200 ng HBs Ag/106 cells x 24 h. EFFECT: strain-producer of antigen and recombinant plasmid indicated above. 1 tbl
| Title |
Year |
Author |
Number |
| RECOMBINANT PLASMID DNA PVAX2 FOR TRANSFER AND EXPRESSION OF HEPATITIS B SURFACE ANTIGEN GENE IN VARIOLOVACCINE VIRUS GENOME AND A STRAIN OF VARIOLOVACCINE VIRUS EXPRESSING THE SURFACE ANTIGEN OF HEPATITIS B VIRUS |
1985 |
- Al'Tshtejn A.D.
- Andzhaparidze O.G.
- Antonova T.P.
- Baev A.A.
- Bendukidze K.A.
- Gorodetskij S.I.
- Zakharova L.G.
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- Pashvykina G.V.
- Fodor I.I.
- Chernos V.I.
|
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| METHOD OF PREPARING SURFACE ANTIGEN OF HEPATITIS B VIRUS (HBS AG), MONOCLONAL ANTIBODIES CB-HEPI, SURFACE ANTIGEN OF HEPATITIS B VIRUS (HBS AG) AND METHOD OF PREPARING HYBRID CLONE 48/1/574 PRODUCING MONOCLONAL ANTIBODIES CB-HEPI |
1992 |
- Verena Lusila Musio Gonsales
- Ehduardo Penton Arias
- Kh'Juvel' Fontirrochi Ehskobar
- Marselo Nasabal' Gal'Ves
- Marta De Gonsales Gr'Ego
- Alekhandro Beldarrain Isnaga
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- Viktoria Ramires Al'Bakhes
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- Luis Ehrrera Martines
- Khose Garsia Suares
- Gustavo De Lja Riva De Lja Riva
- Ramon Aleksis Sant'Jago Avila
- Karlos Duarte Kano
- Lilia Peres Suares
|
RU2128707C1 |
| RECOMBINANT PLASMID DNA PHBS PROVIDING BIOSYNTHESIS OF SURFACE ANTIGEN OF HEPATITIS B VIRUS, METHOD OF CONSTRUCTION OF PLASMID, YEAST STRAIN PICHIA PASTORIS PS103 (PHBS) AS PRODUCER OF INDICATED ANTIGEN |
2000 |
- Padkina M.V.
- Parfenova L.V.
- Sambuk E.V.
- Smirnov M.N.
|
RU2201452C2 |
| RECOMBINANT PLASMID ENCODING HEPATITIS B VIRUS SURFACE ANTIGEN (HBSAG), ITS PREPARING AND YEAST STRAIN HANSENULA POLYMORPHA AS PRODUCER OF HEPATITIS B VIRUS SURFACE ANTIGEN (HBSAG) |
2002 |
- Lunin V.G.
- Timofeeva T.V.
- Suchkov A.V.
|
RU2207374C1 |
| METHOD OF PRODUCING PROTEIN OF SURFACE ANTIGEN OF HEPATITIS B VIRUS |
0 |
- Atsusi Miyanokhara
- Sikateru Nozaki
- Fukusaburo Khamada
- Akio Tokh-E
- Nobuyaa Okhtomo
- Kenisi Matsubara
|
SU1387878A3 |
| RECOMBINANT PLASMID PFS 19 DETERMINING SYNTHESIS OF THE SURFACE ANTIGEN S OF HUMAN VIRUS HEPATITIS B |
1992 |
- Sasnauskas Kjastutis Vlado
- Iomantene Rasa Jono
- Janulajtis Arvidas Andrjaus
- Bumjalis Vladas Vlado
- Vetrinas Aurimas Juozo
|
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| RECOMBINANT PLASMID DNA PTBI-HBSAG COMPRISING CHIMERIC GENE TBI-HBSAG UNDER CONTROL OF SMALLPOX VACCINE PROMOTER P7,5K AND STRAIN OF RECOMBINANT SMALLPOX VACCINE INDUCING IMMUNE RESPONSE AGAINST HIV AND HUMAN HEPATITIS B IN ANIMAL BODY |
2001 |
- Shchelkunov S.N.
- Rjazankin I.A.
- Ageenko V.A.
- Ignat'Ev G.M.
- Babkin I.V.
|
RU2194075C2 |
| RECOMBINANT PLASMID DNA PC-NS3 PROVIDING INTEGRATION OF COMPLEX OF GENES C, PRM, E, NS1, NS 2A, NS 2B, NS3 OF TICK-BORNE ENCEPHALITIS VIRUS IN GENOME OF BOVINE VACCINE VIRUS AND RECOMBINANT STRAIN OF BOVINE VACCINE VIRUS EXPRESSING COMPLEX OF GENES C, PRM, E, NS1, NS 2A, NS2B, NS3 OF TICK-BORNE ENCEPHALITIS VIRUS IN IMMUNIZED ORGANISM CELLS |
1995 |
- Gajnullina M.N.
- Dmitriev I.P.
- Dobrikova E.Ju.
- Khromykh A.A.
- Ignat'Ev G.M.
- Pugachev K.V.
- Ageenko V.A.
- Vorob'Eva M.S.
- Pletnev A.G.
- Beljaev A.S.
- Sandakhchiev L.S.
|
RU2112038C1 |
| RECONBINANT PLASMID DNA P7,5S 11 CME FOR OBTAINING VACCINE AGAINST ENCEPHALITIS AND HAPATITIS |
0 |
- Belyaev A.S.
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- Shevlyagina L.R.
- Baklanov M.M.
- Ammosov A.D.
- Mironova E.B.
- Pletnev A.G.
- Pressman E.K.
- Matveev L.E.
|
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| RECOMBINANT PLASMID DNA PKHBC-33 CONTAINING GENE OF HEPATITIS B VIRUS CORE ANTIGEN INVOLVING SEQUENCE OF THE MAIN NEUTRALIZING EPITOPE OF HEPATITIS B VIRUS SURFACE ANTIGEN (137-147) AND STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF HEPATITIS B VIRUS CORE ANTIGEN WITH THE MAIN NEUTRALIZING EPITOPE OF HEPATITIS B VIRUS SURFACE ANTIGEN EXHIBITED ON ITS SURFACE |
1995 |
- Karpenko L.I.
- Chikaev N.A.
- Melamed N.V.
- Il'Ichev A.A.
- Bajborodin S.I.
|
RU2112039C1 |
